Literature DB >> 2696413

[Neonatal pleuropulmonary staphylococcal infection with multiple abscesses of the liver].

B Guillois, M G Guillemin, M Thoma, J Sizun, J L Monnery, D Alix.   

Abstract

We report the case of a neonate who developed septicemia due to a methicillin-susceptible Staphylococcus aureus strain at six days of age. At eight days of age, physical evaluation revealed a tense, tender abdomen and further enlargement of the liver, and abdominal ultrasonography demonstrated multiple liver abscesses. On the following day, pleuropulmonary lesions developed and required mechanical ventilation. Recovery was achieved using parenteral vancomycin and fosfomycin for 15 days followed by oral pristinamycin for ten days. This case is unusual in that the infection was acquired by the digestive route probably as a result of lymphangitis of the breast in the mother, and multiple liver abscesses were associated with the pleuropulmonary localization. It provides further evidence of the value of ultrasonography for the diagnosis and monitoring of liver abscesses, including multiple abscesses.

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Year:  1989        PMID: 2696413

Source DB:  PubMed          Journal:  Ann Pediatr (Paris)        ISSN: 0066-2097


  2 in total

Review 1.  The Potential Role of Fosfomycin in Neonatal Sepsis Caused by Multidrug-Resistant Bacteria.

Authors:  Grace Li; Joseph F Standing; Julia Bielicki; William Hope; John van den Anker; Paul T Heath; Mike Sharland
Journal:  Drugs       Date:  2017-06       Impact factor: 9.546

2.  Randomised controlled trial of fosfomycin in neonatal sepsis: pharmacokinetics and safety in relation to sodium overload.

Authors:  Christina W Obiero; Phoebe Williams; Sheila Murunga; Johnstone Thitiri; Raymond Omollo; Ann Sarah Walker; Thaddaeus Egondi; Borna Nyaoke; Erika Correia; Zoe Kane; Silke Gastine; Karin Kipper; Joseph F Standing; Sally Ellis; Mike Sharland; James Alexander Berkley
Journal:  Arch Dis Child       Date:  2022-01-25       Impact factor: 4.920

  2 in total

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