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Literature DB >> 26963555

Cas9 loosens its grip on off-target sites.

Christopher E Nelson¹, Charles A Gersbach¹.

Abstract

Mesh：

Substances：

Year: 2016 PMID： 26963555 DOI： 10.1038/nbt.3501

Source DB: PubMed Journal: Nat Biotechnol ISSN： 1087-0156 Impact factor: 54.908

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10 in total

Review 1. Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.

Authors: Mehmet Fatih Bolukbasi; Ankit Gupta; Scot A Wolfe
Journal: Nat Methods Date: 2016-01 Impact factor: 28.547

Review 2. Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

Authors: Jennifer A Doudna; Emmanuelle Charpentier
Journal: Science Date: 2014-11-28 Impact factor: 47.728

3. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Authors: Christopher E Nelson; Chady H Hakim; David G Ousterout; Pratiksha I Thakore; Eirik A Moreb; Ruth M Castellanos Rivera; Sarina Madhavan; Xiufang Pan; F Ann Ran; Winston X Yan; Aravind Asokan; Feng Zhang; Dongsheng Duan; Charles A Gersbach
Journal: Science Date: 2015-12-31 Impact factor: 47.728

4. Rationally engineered Cas9 nucleases with improved specificity.

Authors: Ian M Slaymaker; Linyi Gao; Bernd Zetsche; David A Scott; Winston X Yan; Feng Zhang
Journal: Science Date: 2015-12-01 Impact factor: 47.728

Review 5. Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

Authors: Pratiksha I Thakore; Joshua B Black; Isaac B Hilton; Charles A Gersbach
Journal: Nat Methods Date: 2016-02 Impact factor: 28.547

6. In vivo genome editing using Staphylococcus aureus Cas9.

Authors: F Ann Ran; Le Cong; Winston X Yan; David A Scott; Jonathan S Gootenberg; Andrea J Kriz; Bernd Zetsche; Ophir Shalem; Xuebing Wu; Kira S Makarova; Eugene V Koonin; Phillip A Sharp; Feng Zhang
Journal: Nature Date: 2015-04-01 Impact factor: 49.962

Review 7. Genome-editing Technologies for Gene and Cell Therapy.

Authors: Morgan L Maeder; Charles A Gersbach
Journal: Mol Ther Date: 2016-01-12 Impact factor: 11.454

8. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.

Authors: Yanfang Fu; Jeffry D Sander; Deepak Reyon; Vincent M Cascio; J Keith Joung
Journal: Nat Biotechnol Date: 2014-01-26 Impact factor: 54.908

9. Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

Authors: Carolin Anders; Ole Niewoehner; Alessia Duerst; Martin Jinek
Journal: Nature Date: 2014-07-27 Impact factor: 49.962

10. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

Authors: Benjamin P Kleinstiver; Vikram Pattanayak; Michelle S Prew; Shengdar Q Tsai; Nhu T Nguyen; Zongli Zheng; J Keith Joung
Journal: Nature Date: 2016-01-06 Impact factor: 49.962

10 in total

5 in total

Cas9 loosens its grip on off-target sites.

Review 1. Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery.

Review 2. Genome editing. The new frontier of genome engineering with CRISPR-Cas9.

3. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

4. Rationally engineered Cas9 nucleases with improved specificity.

Review 5. Editing the epigenome: technologies for programmable transcription and epigenetic modulation.

6. In vivo genome editing using Staphylococcus aureus Cas9.

Review 7. Genome-editing Technologies for Gene and Cell Therapy.

8. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.

9. Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

10. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

1. The evolving EU regulatory framework for precision breeding.

Review 2. New CRISPR Tools to Correct Pathogenic Mutations in Usher Syndrome.

Review 3. Optimization of genome editing through CRISPR-Cas9 engineering.

4. CRISPR-SKIP: programmable gene splicing with single base editors.

Review 5. Methods and applications of CRISPR/Cas system for genome editing in stem cells.