Literature DB >> 26962405

Efficiency and patient experience with propofol vs conventional sedation: A prospective study.

Patrick Thornley1, Mohammad Al Beshir1, James Gregor1, Andreas Antoniou1, Nitin Khanna1.   

Abstract

AIM: To determine whether anaesthesiologist-administered sedation with propofol (AAP) or endoscopist-administered conscious sedation (EAC) with fentanyl/midazolam shortens colonoscopy duration/total room time.
METHODS: This is a prospective, non-randomized, comparative study that enrolled patients greater than 18 years of age undergoing colonoscopy in a single Canadian academic outpatient endoscopy unit over a three-month consecutive period. Colonoscopies in this unit are performed both with AAP and EAC. Patient demographics, procedure-related data and adverse events were documented. Additionally, the level of procedure difficulty, and whether a staff endoscopist, trainee with assistance, or independent trainee, performed the procedure were documented. A validated modified 4-question, 5-point Likert scale telephone survey was used to assess patient satisfaction with colonoscopy. The telephone patient satisfaction survey was conducted 24-72 h following the procedure.
RESULTS: Two hundred and thirty patients were enrolled during the study period with 126 patients in the AAP group and 104 patients in the EAC group. Mean procedure time was 18.3 ± 10.1 min in the AAP group and 14.7 ± 7.1 min in the EAC group (P = 0.002). Mean total room time was 36.8 ± 13.7 with AAP and 30.1 ± 11 min with EAC (P < 0.001). Multivariate analysis revealed the use of AAP (P = 0.002), resident participation (P < 0.001), diagnostic interventions (P = 0.033), therapeutic interventions (P < 0.001), lower body mass index (P = 0.008) and American Society of Anaesthesiologist class (P = 0.016), to be predictors of longer total room time. Patient age and gender were not significant predictors. After excluding cases in which trainees were involved, there was no significant difference in procedure time between the two groups (P = 0.941), however total room time was still prolonged in the AAP group (P = 0.019). The amount of pain experienced was lower with AAP (P = 0.02), with a trend toward overall higher patient satisfaction (P = 0.074). There were 2 sedation-related adverse events, both in the AAP group involving a patient with aspiration requiring hospitalization and a patient with hypoxia managed with bronchodilators.
CONCLUSION: EAC results in reduced total room time compared to AAP. Resident participation doubles procedure time regardless of sedation type.

Entities:  

Keywords:  Colonoscopy; Fentanyl; Midazolam; Patient satisfaction; Propofol

Year:  2016        PMID: 26962405      PMCID: PMC4766256          DOI: 10.4253/wjge.v8.i4.232

Source DB:  PubMed          Journal:  World J Gastrointest Endosc


  19 in total

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2.  Endoscopy unit efficiency: quality redefined.

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4.  Canadian consensus on medically acceptable wait times for digestive health care.

Authors:  William G Paterson; William T Depew; Pierre Paré; Denis Petrunia; Connie Switzer; Sander J Veldhuyzen van Zanten; Sandra Daniels
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5.  Trained registered nurses/endoscopy teams can administer propofol safely for endoscopy.

Authors:  Douglas K Rex; Ludwig T Heuss; John A Walker; Rong Qi
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6.  Endoscopic sedation in the United States: results from a nationwide survey.

Authors:  Lawrence B Cohen; Julie S Wecsler; John N Gaetano; Ariel A Benson; Kenneth M Miller; Valerie Durkalski; James Aisenberg
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7.  Does sedation type affect colonoscopy perforation rates?

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8.  Effect of propofol anesthesia on force application during colonoscopy.

Authors:  Louis Y Korman; Nadim G Haddad; David C Metz; Lawrence J Brandt; Stanley B Benjamin; Susan K Lazerow; Hannah L Miller; Mihriye Mete; Milind Patel; Vladimir Egorov
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Review 9.  Endoscopist-directed administration of propofol: a worldwide safety experience.

Authors:  Douglas K Rex; Viju P Deenadayalu; Emely Eid; Thomas F Imperiale; John A Walker; Kuldip Sandhu; Anthony C Clarke; Lybus C Hillman; Akira Horiuchi; Lawrence B Cohen; Ludwig T Heuss; Shajan Peter; Christoph Beglinger; James A Sinnott; Thomas Welton; Magdy Rofail; Iyad Subei; Rodger Sleven; Paul Jordan; John Goff; Patrick D Gerstenberger; Harold Munnings; Martin Tagle; Brian W Sipe; Till Wehrmann; Jack A Di Palma; Kaitlin E Occhipinti; Egidio Barbi; Andrea Riphaus; Stephen T Amann; Gen Tohda; Timothy McClellan; Charles Thueson; John Morse; Nizam Meah
Journal:  Gastroenterology       Date:  2009-06-21       Impact factor: 22.682

Review 10.  Propofol for sedation during colonoscopy.

Authors:  Harminder Singh; William Poluha; Mary Cheung; Nicole Choptain; Ken I Baron; Shayne P Taback
Journal:  Cochrane Database Syst Rev       Date:  2008-10-08
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1.  Patient satisfaction and safety profile with sedation during gastrointestinal endoscopy.

Authors:  Nimesh K Tarway; Mayank Jain; V P Rajavel; Srinivas Melpakkam; Vijaya Srinivasan; R Ravi; Joy Varghese; Tom Michael; Jayanthi Venkataraman
Journal:  Indian J Gastroenterol       Date:  2017-07

2.  No increased risk of perforation during colonoscopy in patients undergoing propofol versus traditional sedation: A meta-analysis.

Authors:  Minmin Xue; Jian Tian; Jing Zhang; Hongbin Zhu; Jun Bai; Sujuan Zhang; Qili Wang; Shuge Wang; Xuzheng Song; Donghong Ma; Jia Li; Yongmin Zhang; Wei Li; Dongxu Wang
Journal:  Indian J Gastroenterol       Date:  2018-03-09

3.  Propofol sedation and colonoscopy: a perspective from endoscopists.

Authors:  David E Pace; Mark R Borgaonkar
Journal:  CMAJ       Date:  2018-11-19       Impact factor: 8.262

4.  Effects of Bispectral Index-controlled Use of Magnesium on Propofol Consumption and Sedation Level in Patients Undergoing Colonoscopy.

Authors:  Hamit Yoldas; Isa Yildiz; Ibrahim Karagoz; Mustafa Sit; Muhammed Nur Ogun; Abdullah Demirhan; Murat Bilgi
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5.  Paradigm shift: should the elderly undergo propofol sedation for DBE? A prospective cohort study.

Authors:  Hey-Long Ching; Federica Branchi; David S Sanders; David Turnbull; Reena Sidhu
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  5 in total

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