Literature DB >> 2696193

Failure of cytotoxic chemotherapy, 1983-1988, and the emerging role of monoclonal antibodies for renal cancer.

A Yagoda1, N H Bander.   

Abstract

A review of 36 cytotoxic agents used singly in over 1,900 patients with renal cancer between 1983 and 1988 finds marginal antitumor activity, less than 5-10%. The future role of monoclonal antibodies for therapy of this disease may offer some hope with the recent description of rather specific phenotypic expression, URO 10+/URO 8+, suggesting the cell origin of most renal tumors from the distal portion of the proximal tubule.

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Year:  1989        PMID: 2696193     DOI: 10.1159/000281537

Source DB:  PubMed          Journal:  Urol Int        ISSN: 0042-1138            Impact factor:   2.089


  16 in total

1.  Sinonasal Metastatic Renal Cell Carcinoma: A Report of Two Cases with Varied Presentation and a Review of Literature.

Authors:  Pooja Dalakoti; Kailesh Pujary; Balakrishnan Ramaswamy
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2018-08-24

Review 2.  Perspectives in drug development for metastatic renal cell cancer.

Authors:  Bristi Basu; Tim Eisen
Journal:  Target Oncol       Date:  2010-08-06       Impact factor: 4.493

3.  Gemcitabine: a phase II study in patients with advanced renal cancer.

Authors:  P H De Mulder; L Weissbach; G Jakse; R Osieka; J Blatter
Journal:  Cancer Chemother Pharmacol       Date:  1996       Impact factor: 3.333

4.  Systemic therapy for advanced renal cell carcinoma.

Authors:  James M G Larkin; Emma L S Kipps; Ceri J Powell; Charles Swanton
Journal:  Ther Adv Med Oncol       Date:  2009-07       Impact factor: 8.168

Review 5.  Anti-Cancer Drug Validation: the Contribution of Tissue Engineered Models.

Authors:  Mariana R Carvalho; Daniela Lima; Rui L Reis; Joaquim M Oliveira; Vitor M Correlo
Journal:  Stem Cell Rev Rep       Date:  2017-06       Impact factor: 5.739

6.  Ifosfamide, vindesine and recombinant alpha-interferon combination chemotherapy for metastatic renal cell carcinoma.

Authors:  H J König; W Gutmann; J Weissmüller
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

7.  Inter and intratumour heterogeneity: a barrier to individualized medical therapy in renal cell carcinoma?

Authors:  Rosalie Fisher; James Larkin; Charles Swanton
Journal:  Front Oncol       Date:  2012-05-18       Impact factor: 6.244

8.  Delivering preventive, predictive and personalised cancer medicine for renal cell carcinoma: the challenge of tumour heterogeneity.

Authors:  Rosalie Fisher; James Larkin; Charles Swanton
Journal:  EPMA J       Date:  2011-12-22       Impact factor: 6.543

9.  Host humoral and cellular immune mechanisms in the continued suppression of Friend erythroleukemia metastases after interferon alpha/beta treatment in mice.

Authors:  I Gresser; C Carnaud; C Maury; A Sala; P Eid; D Woodrow; M T Maunoury; F Belardelli
Journal:  J Exp Med       Date:  1991-05-01       Impact factor: 14.307

10.  Renal cell carcinoma and the use of sorafenib.

Authors:  James Mg Larkin; Tim Eisen
Journal:  Ther Clin Risk Manag       Date:  2006-03       Impact factor: 2.423

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