Literature DB >> 26958307

Translational Meta-analytical Methods to Localize the Regulatory Patterns of Neurological Disorders in the Human Brain.

Vanessa Sochat1, Maude David2, Dennis P Wall1.   

Abstract

The task of mapping neurological disorders in the human brain must be informed by multiple measurements of an individual's phenotype - neuroimaging, genomics, and behavior. We developed a novel meta-analytical approach to integrate disparate resources and generated transcriptional maps of neurological disorders in the human brain yielding a purely computational procedure to pinpoint the brain location of transcribed genes likely to be involved in either onset or maintenance of the neurological condition.

Entities:  

Mesh：

Year:  2015        PMID： 26958307      PMCID： PMC4765688     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN： 1559-4076


  55 in total

1.  KEGG: kyoto encyclopedia of genes and genomes.

Authors:  M Kanehisa; S Goto
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

Review 2.  Whole-genome analyses of whole-brain data: working within an expanded search space.

Authors:  Sarah E Medland; Neda Jahanshad; Benjamin M Neale; Paul M Thompson
Journal:  Nat Neurosci       Date:  2014-05-27       Impact factor: 24.884

3.  Overreactive brain responses to sensory stimuli in youth with autism spectrum disorders.

Authors:  Shulamite A Green; Jeffrey D Rudie; Natalie L Colich; Jeffrey J Wood; David Shirinyan; Leanna Hernandez; Nim Tottenham; Mirella Dapretto; Susan Y Bookheimer
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2013-08-24       Impact factor: 8.829

4.  Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Authors:  Aravind Subramanian; Pablo Tamayo; Vamsi K Mootha; Sayan Mukherjee; Benjamin L Ebert; Michael A Gillette; Amanda Paulovich; Scott L Pomeroy; Todd R Golub; Eric S Lander; Jill P Mesirov
Journal:  Proc Natl Acad Sci U S A       Date:  2005-09-30       Impact factor: 11.205

5.  Brain function differences in language processing in children and adults with autism.

Authors:  Diane L Williams; Vladimir L Cherkassky; Robert A Mason; Timothy A Keller; Nancy J Minshew; Marcel Adam Just
Journal:  Autism Res       Date:  2013-03-14       Impact factor: 5.216

6.  Underconnectivity between voice-selective cortex and reward circuitry in children with autism.

Authors:  Daniel A Abrams; Charles J Lynch; Katherine M Cheng; Jennifer Phillips; Kaustubh Supekar; Srikanth Ryali; Lucina Q Uddin; Vinod Menon
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-17       Impact factor: 11.205

7.  Network-based analysis reveals stronger local diffusion-based connectivity and different correlations with oral language skills in brains of children with high functioning autism spectrum disorders.

Authors:  Hai Li; Zhong Xue; Timothy M Ellmore; Richard E Frye; Stephen T C Wong
Journal:  Hum Brain Mapp       Date:  2012-09-24       Impact factor: 5.038

8.  Selective cerebral volume reduction in Rett syndrome: a multiple-approach MR imaging study.

Authors:  J C Carter; D C Lanham; D Pham; G Bibat; S Naidu; W E Kaufmann
Journal:  AJNR Am J Neuroradiol       Date:  2007-12-07       Impact factor: 3.825

9.  Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

Authors:  W J Strittmatter; A M Saunders; D Schmechel; M Pericak-Vance; J Enghild; G S Salvesen; A D Roses
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-01       Impact factor: 11.205

10.  The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism.

Authors:  A Di Martino; C-G Yan; Q Li; E Denio; F X Castellanos; K Alaerts; J S Anderson; M Assaf; S Y Bookheimer; M Dapretto; B Deen; S Delmonte; I Dinstein; B Ertl-Wagner; D A Fair; L Gallagher; D P Kennedy; C L Keown; C Keysers; J E Lainhart; C Lord; B Luna; V Menon; N J Minshew; C S Monk; S Mueller; R-A Müller; M B Nebel; J T Nigg; K O'Hearn; K A Pelphrey; S J Peltier; J D Rudie; S Sunaert; M Thioux; J M Tyszka; L Q Uddin; J S Verhoeven; N Wenderoth; J L Wiggins; S H Mostofsky; M P Milham
Journal:  Mol Psychiatry       Date:  2013-06-18       Impact factor: 15.992
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