Michael Olamoyegun1, Waheed Ibraheem2, Sandra Iwuala3, Morenike Audu4, Babatope Kolawole5. 1. LAUTECH Teaching Hospital, and College of Health Sciences, Ladoke Akintola University of Technology, Department of Internal Medicine; Endocrinology, Diabetes & Metabolism Unit. 2. LAUTECH Teaching Hospital, Ogbomoso, Ophthalmology. 3. College of Medicine, University of Lagos, Lagos University Teaching Hospital, Idi- Araba, Lagos Department of Medicine, Endocrinology, Diabetes & Metabolism Unit. 4. LAUTECH Teaching Hospital, Ogbomoso, Oyo State, Department of Internal Medicine. 5. Obafemi Awolowo University, Dept of Medicine.
Abstract
INTRODUCTION: Diabetes mellitus (DM) afflicts at least 5 million people in Nigeria, with more than 80% having type 2 diabetes mellitus (T2DM). Microvascular complications increase both morbidity and mortality inpatients with T2DM. The aims of this study were to report the burden of various microvascular complications in T2DM and to identify various factors associated with these complications in patients with T2DM attending the diabetes outpatients' clinic. METHODS: Ninety (90) patients with T2DM who have attended diabetes clinic for at least 3 months were recruited for this study. Detailed history, physical examination and biochemical analysis was done in each of the patients. All patients underwent a detailed standard evaluation to detect diabetic retinopathy (fundoscopy), neuropathy (10g monofilament and/or diabetes neuropathy scores), and nephropathy (microalbuminuria, macroalbuminuria, serum creatinine and estimated glomerular filtration rate). RESULTS: There was high prevalence of microvascular complications among patients with T2DM. Almost half of patients with T2DM had some form of microvascular complications; diabetic neuropathy being the commonest (69.6%),followed by nephropathy (54.5%) and retinopathy (48.9%). The factors associated with developing these complications were increasing age, duration of diabetes, hypertension and dyslipidaemia for nephropathy and neuropathy. CONCLUSION: There is a high burden of microvascular complications in patients with type 2 diabetes. Age, male gender, hypertension, glycaemic control, BMI and duration of diabetes, and glycaemic control were factors associated with microvasular complications.
INTRODUCTION:Diabetes mellitus (DM) afflicts at least 5 million people in Nigeria, with more than 80% having type 2 diabetes mellitus (T2DM). Microvascular complications increase both morbidity and mortality inpatients with T2DM. The aims of this study were to report the burden of various microvascular complications in T2DM and to identify various factors associated with these complications in patients with T2DM attending the diabetes outpatients' clinic. METHODS: Ninety (90) patients with T2DM who have attended diabetes clinic for at least 3 months were recruited for this study. Detailed history, physical examination and biochemical analysis was done in each of the patients. All patients underwent a detailed standard evaluation to detect diabetic retinopathy (fundoscopy), neuropathy (10g monofilament and/or diabetes neuropathy scores), and nephropathy (microalbuminuria, macroalbuminuria, serum creatinine and estimated glomerular filtration rate). RESULTS: There was high prevalence of microvascular complications among patients with T2DM. Almost half of patients with T2DM had some form of microvascular complications; diabetic neuropathy being the commonest (69.6%),followed by nephropathy (54.5%) and retinopathy (48.9%). The factors associated with developing these complications were increasing age, duration of diabetes, hypertension and dyslipidaemia for nephropathy and neuropathy. CONCLUSION: There is a high burden of microvascular complications in patients with type 2 diabetes. Age, male gender, hypertension, glycaemic control, BMI and duration of diabetes, and glycaemic control were factors associated with microvasular complications.
Entities:
Keywords:
Nigeria; Type 2 diabetes; microvascular complications; prevalence; risk factors
Authors: Luis Miguel Román-Pintos; Geannyne Villegas-Rivera; Adolfo Daniel Rodríguez-Carrizalez; Alejandra Guillermina Miranda-Díaz; Ernesto Germán Cardona-Muñoz Journal: J Diabetes Res Date: 2016-12-12 Impact factor: 4.011
Authors: Kenneth Ekoru; Ayo Doumatey; Amy R Bentley; Guanjie Chen; Jie Zhou; Daniel Shriner; Olufemi Fasanmade; Godfrey Okafor; Benjamin Eghan; Kofi Agyenim-Boateng; Jokotade Adeleye; Williams Balogun; Albert Amoah; Joseph Acheampong; Thomas Johnson; Johnnie Oli; Clement Adebamowo; Francis Collins; Georgia Dunston; Adebowale Adeyemo; Charles Rotimi Journal: EClinicalMedicine Date: 2019-10-17