The effects of cancer therapy on women's fertility: what do we know now?

Due to the improvements of cancer treatment, the survival rate of cancer increased over the last decades. One of the detrimental side effects of cytotoxic treatment is the impairment or loss of fertility. Having a family is one of the important aspects for long-time survivors. The impact of gynecologic cancer on fertility depends on the site and kind of the cancer disease, the oncologic therapeutic regimen and additional the age of the patient. In cancer of the internal genital organs, fertility-preserving surgery techniques should be used, if possible. In case, that cytotoxic treatment has to be applied, fertility preservation techniques should be implemented into the oncologic treatment.