Literature DB >> 26954515

Site-specific conjugation of single domain antibodies to liposomes enhances photosensitizer uptake and photodynamic therapy efficacy.

M Broekgaarden1, R van Vught2, S Oliveira3, R C Roovers3, P M P van Bergen en Henegouwen3, R J Pieters4, T M Van Gulik1, E Breukink2, M Heger1.   

Abstract

Photodynamic therapy for therapy-resistant cancers will greatly benefit from targeted delivery of tumor photosensitizing agents. In this study, a strategy for the site-specific conjugation of single domain antibodies onto liposomes containing the photosensitizer zinc phthalocyanine was developed and tested.

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Year:  2016        PMID: 26954515     DOI: 10.1039/c6nr00014b

Source DB:  PubMed          Journal:  Nanoscale        ISSN: 2040-3364            Impact factor:   7.790


  9 in total

1.  Impacting Pancreatic Cancer Therapy in Heterotypic in Vitro Organoids and in Vivo Tumors with Specificity-Tuned, NIR-Activable Photoimmunonanoconjugates: Towards Conquering Desmoplasia?

Authors:  Girgis Obaid; Shazia Bano; Srivalleesha Mallidi; Mans Broekgaarden; Jerrin Kuriakose; Zachary Silber; Anne-Laure Bulin; Yucheng Wang; Zhiming Mai; Wendong Jin; Diane Simeone; Tayyaba Hasan
Journal:  Nano Lett       Date:  2019-10-04       Impact factor: 11.189

2.  Application of Monolayer Cell Cultures for Investigating Basic Mechanisms of Photodynamic Therapy.

Authors:  Mans Broekgaarden
Journal:  Methods Mol Biol       Date:  2022

Review 3.  Photodynamic Therapy and the Biophysics of the Tumor Microenvironment.

Authors:  Aaron J Sorrin; Mustafa Kemal Ruhi; Nathaniel A Ferlic; Vida Karimnia; William J Polacheck; Jonathan P Celli; Huang-Chiao Huang; Imran Rizvi
Journal:  Photochem Photobiol       Date:  2020-03-05       Impact factor: 3.421

Review 4.  A review and outlook in the treatment of osteosarcoma and other deep tumors with photodynamic therapy: from basic to deep.

Authors:  Wei Yu; Jian Zhu; Yitian Wang; Junjie Wang; Weijing Fang; Kaishun Xia; Jianlin Shao; Minzu Wu; Bing Liu; Chengzhen Liang; Chengyi Ye; Huimin Tao
Journal:  Oncotarget       Date:  2017-06-13

5.  Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids.

Authors:  Mans Broekgaarden; Imran Rizvi; Anne-Laure Bulin; Ljubica Petrovic; Ruth Goldschmidt; Iqbal Massodi; Jonathan P Celli; Tayyaba Hasan
Journal:  Oncotarget       Date:  2018-02-06

6.  Multi-OMIC profiling of survival and metabolic signaling networks in cells subjected to photodynamic therapy.

Authors:  Ruud Weijer; Séverine Clavier; Esther A Zaal; Maud M E Pijls; Robert T van Kooten; Klaas Vermaas; René Leen; Aldo Jongejan; Perry D Moerland; Antoine H C van Kampen; André B P van Kuilenburg; Celia R Berkers; Simone Lemeer; Michal Heger
Journal:  Cell Mol Life Sci       Date:  2016-11-01       Impact factor: 9.261

Review 7.  Site-specific pharmaco-laser therapy: A novel treatment modality for refractory port wine stains.

Authors:  M Ingmar van Raath; Jojanneke E van Amesfoort; Martin Hermann; Yasin Ince; Maurice J Zwart; Agustina V Echague; Yan Chen; Baoyue Ding; Xuan Huang; Gert Storm; Michal Heger
Journal:  J Clin Transl Res       Date:  2019-05-01

Review 8.  Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery.

Authors:  Bethany Almeida; Okhil K Nag; Katherine E Rogers; James B Delehanty
Journal:  Molecules       Date:  2020-12-01       Impact factor: 4.411

Review 9.  Multi-Functional Liposome: A Powerful Theranostic Nano-Platform Enhancing Photodynamic Therapy.

Authors:  Xiamin Cheng; Jing Gao; Yang Ding; Yao Lu; Qiancheng Wei; Dezhi Cui; Jiali Fan; Xiaoman Li; Ershu Zhu; Yongna Lu; Qiong Wu; Lin Li; Wei Huang
Journal:  Adv Sci (Weinh)       Date:  2021-06-03       Impact factor: 16.806

  9 in total

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