| Literature DB >> 26953773 |
Shan Zhao1, Jianye Dai1, Mo Hu2, Chang Liu2, Rong Meng2, Xiaoyun Liu2, Chu Wang1, Tuoping Luo1.
Abstract
The photo-induced reactions of diaryltetrazoles with carboxylic acids in aqueous solution were investigated. Besides measuring the apparent second-order rate constant and evaluating the functional group compatibility of these reactions, we further incorporated the tetrazoles into SAHA, leading to a new active-site-directed probe for labelling HDACs in both cell lysates and living cells.Entities:
Mesh:
Substances:
Year: 2016 PMID: 26953773 DOI: 10.1039/c5cc10445a
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222