Literature DB >> 26952843

STAT3 inhibitor has potent antitumor activity in B-lineage acute lymphoblastic leukemia cells overexpressing the high mobility group A1 (HMGA1)-STAT3 pathway.

Amy Belton1, Lingling Xian1, Tait Huso1, Michael Koo1, Li Z Luo1, James Turkson2, Brent D G Page3, Patrick T Gunning3, Guosheng Liu4, David L Huso4,5, Linda M S Resar1,5.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26952843      PMCID： PMC5580963          DOI： 10.3109/10428194.2016.1153089

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


× No keyword cloud information.
  15 in total

1.  Flavopiridol induces BCL-2 expression and represses oncogenic transcription factors in leukemic blasts from adults with refractory acute myeloid leukemia.

Authors:  Dwella M Nelson; Biju Joseph; Joelle Hillion; Jodi Segal; Judith E Karp; Linda M S Resar
Journal:  Leuk Lymphoma       Date:  2011-07-05

2.  Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts.

Authors:  Xiaolei Zhang; Peibin Yue; Brent D G Page; Tianshu Li; Wei Zhao; Andrew T Namanja; David Paladino; Jihe Zhao; Yuan Chen; Patrick T Gunning; James Turkson
Journal:  Proc Natl Acad Sci U S A       Date:  2012-05-23       Impact factor: 11.205

3.  Nanoparticle delivery of inhibitory signal transducer and activator of transcription 3 G-quartet oligonucleotides blocks tumor growth in HMGA1 transgenic model of T-cell leukemia.

Authors:  Joelle Hillion; Amy M Belton; Sandeep N Shah; James Turkson; Naijie Jing; David J Tweardy; Francescopaolo di Cello; David L Huso; Linda M S Resar
Journal:  Leuk Lymphoma       Date:  2013-08-13

4.  HMG-I/Y, a new c-Myc target gene and potential oncogene.

Authors:  L J Wood; M Mukherjee; C E Dolde; Y Xu; J F Maher; T E Bunton; J B Williams; L M Resar
Journal:  Mol Cell Biol       Date:  2000-08       Impact factor: 4.272

5.  The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?

Authors:  Joelle Hillion; Surajit Dhara; Takita Felder Sumter; Mita Mukherjee; Francescopaolo Di Cello; Amy Belton; James Turkson; Souyma Jaganathan; Linzhao Cheng; Zhaohui Ye; Richard Jove; Peter Aplan; Ying-Wei Lin; Kelsey Wertzler; Ray Reeves; Ossama Elbahlouh; Jeanne Kowalski; Raka Bhattacharya; Linda M S Resar
Journal:  Cancer Res       Date:  2008-12-15       Impact factor: 12.701

Review 6.  Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia.

Authors:  Stephen P Hunger; Mignon L Loh; James A Whitlock; Naomi J Winick; William L Carroll; Meenakshi Devidas; Elizabeth A Raetz
Journal:  Pediatr Blood Cancer       Date:  2012-12-19       Impact factor: 3.167

7.  HMGA1 overexpression correlates with relapse in childhood B-lineage acute lymphoblastic leukemia.

Authors:  Sujayita Roy; Francescopaolo Di Cello; Jeanne Kowalski; Alexandra C Hristov; Hua-Ling Tsai; Deepa Bhojwani; Julia A Meyer; William L Carroll; Amy Belton; Linda M S Resar
Journal:  Leuk Lymphoma       Date:  2013-04-30

8.  Hierarchical maintenance of MLL myeloid leukemia stem cells employs a transcriptional program shared with embryonic rather than adult stem cells.

Authors:  Tim C P Somervaille; Christina J Matheny; Gary J Spencer; Masayuki Iwasaki; John L Rinn; Daniela M Witten; Howard Y Chang; Sheila A Shurtleff; James R Downing; Michael L Cleary
Journal:  Cell Stem Cell       Date:  2009-02-06       Impact factor: 24.633

9.  HMGA1 reprograms somatic cells into pluripotent stem cells by inducing stem cell transcriptional networks.

Authors:  Sandeep N Shah; Candace Kerr; Leslie Cope; Elias Zambidis; Cyndi Liu; Joelle Hillion; Amy Belton; David L Huso; Linda M S Resar
Journal:  PLoS One       Date:  2012-11-15       Impact factor: 3.240

10.  HMGA1 induces intestinal polyposis in transgenic mice and drives tumor progression and stem cell properties in colon cancer cells.

Authors:  Amy Belton; Alexander Gabrovsky; Young Kyung Bae; Ray Reeves; Christine Iacobuzio-Donahue; David L Huso; Linda M S Resar
Journal:  PLoS One       Date:  2012-01-20       Impact factor: 3.240
View more
  6 in total

Review 1.  The High Mobility Group A1 (HMGA1) Transcriptome in Cancer and Development.

Authors:  T F Sumter; L Xian; T Huso; M Koo; Y-T Chang; T N Almasri; L Chia; C Inglis; D Reid; L M S Resar
Journal:  Curr Mol Med       Date:  2016       Impact factor: 2.222

2.  MicroRNA-296-5p inhibits cell proliferation by targeting HMGA1 in colorectal cancer.

Authors:  Guohui Yan; Shuidi Yan; Jiajia Wang; Shen Lei; Weimin Tian; Xin Yue; Yang Zhang
Journal:  Exp Ther Med       Date:  2021-05-24       Impact factor: 2.447

Review 3.  Lessons from the Crypt: HMGA1-Amping up Wnt for Stem Cells and Tumor Progression.

Authors:  Linda Resar; Lionel Chia; Lingling Xian
Journal:  Cancer Res       Date:  2018-04-04       Impact factor: 12.701

4.  KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity.

Authors:  Kai Teng; Shi Wei; Chi Zhang; Jiewei Chen; Jinbin Chen; Kanghua Xiao; Jun Liu; Miaomiao Dai; Xinyuan Guan; Jingping Yun; Dan Xie
Journal:  J Exp Clin Cancer Res       Date:  2019-07-24

Review 5.  Clinical Implications of Extracellular HMGA1 in Breast Cancer.

Authors:  Olga Méndez; José Pérez; Jesus Soberino; Fabricio Racca; Javier Cortés; Josep Villanueva
Journal:  Int J Mol Sci       Date:  2019-11-26       Impact factor: 5.923

Review 6.  The Role of Janus Kinase/STAT3 Pathway in Hematologic Malignancies With an Emphasis on Epigenetics.

Authors:  Elham Zeinalzadeh; Alexey Valerievich Yumashev; Heshu Sulaiman Rahman; Faroogh Marofi; Navid Shomali; Hossein Samadi Kafil; Saeed Solali; Mehdi Sajjadi-Dokht; Sajjad Vakili-Samiani; Mostafa Jarahian; Majid Farshdousti Hagh
Journal:  Front Genet       Date:  2021-12-21       Impact factor: 4.599
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.