Literature DB >> 26952837

CXCL12 promotes glycolytic reprogramming in acute myeloid leukemia cells via the CXCR4/mTOR axis.

M Braun1, M Qorraj1, M Büttner2, F A Klein3, D Saul1, M Aigner1, W Huber3, A Mackensen1, R Jitschin1, D Mougiakakos1.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26952837     DOI： 10.1038/leu.2016.58

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


× No keyword cloud information.
  15 in total

1.  A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia.

Authors:  Geoffrey L Uy; Michael P Rettig; Ibraheem H Motabi; Kyle McFarland; Kathryn M Trinkaus; Lindsay M Hladnik; Shashikant Kulkarni; Camille N Abboud; Amanda F Cashen; Keith E Stockerl-Goldstein; Ravi Vij; Peter Westervelt; John F DiPersio
Journal:  Blood       Date:  2012-02-02       Impact factor: 22.113

2.  Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5).

Authors:  S M Garrido; F R Appelbaum; C L Willman; D E Banker
Journal:  Exp Hematol       Date:  2001-04       Impact factor: 3.084

3.  CXCR4 is a prognostic marker in acute myelogenous leukemia.

Authors:  Anke C Spoo; Michael Lübbert; William G Wierda; Jan A Burger
Journal:  Blood       Date:  2006-08-03       Impact factor: 22.113

4.  Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment.

Authors:  Zhihong Zeng; Yue Xi Shi; Twee Tsao; YiHua Qiu; Steven M Kornblau; Keith A Baggerly; Wenbin Liu; Katti Jessen; Yi Liu; Hagop Kantarjian; Christian Rommel; David A Fruman; Michael Andreeff; Marina Konopleva
Journal:  Blood       Date:  2012-07-23       Impact factor: 22.113

5.  Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin.

Authors:  Lauren J Akers; Wendy Fang; Alejandro G Levy; Anna R Franklin; Peng Huang; Patrick A Zweidler-McKay
Journal:  Leuk Res       Date:  2011-02-12       Impact factor: 3.156

6.  CXCR4 regulates migration and development of human acute myelogenous leukemia stem cells in transplanted NOD/SCID mice.

Authors:  Sigal Tavor; Isabelle Petit; Svetlana Porozov; Abraham Avigdor; Ayelet Dar; Leonor Leider-Trejo; Noga Shemtov; Varda Deutsch; Ella Naparstek; Arnon Nagler; Tsvee Lapidot
Journal:  Cancer Res       Date:  2004-04-15       Impact factor: 12.701

7.  The warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation.

Authors:  Ismael Samudio; Michael Fiegl; Teresa McQueen; Karen Clise-Dwyer; Michael Andreeff
Journal:  Cancer Res       Date:  2008-07-01       Impact factor: 12.701

8.  A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value.

Authors:  Wen-Lian Chen; Jing-Han Wang; Ai-Hua Zhao; Xin Xu; Yi-Huang Wang; Tian-Lu Chen; Jun-Min Li; Jian-Qing Mi; Yong-Mei Zhu; Yuan-Fang Liu; Yue-Ying Wang; Jie Jin; He Huang; De-Pei Wu; Yan Li; Xiao-Jing Yan; Jin-Song Yan; Jian-Yong Li; Shuai Wang; Xiao-Jun Huang; Bing-Shun Wang; Zhu Chen; Sai-Juan Chen; Wei Jia
Journal:  Blood       Date:  2014-07-08       Impact factor: 22.113

Review 9.  Contribution of bone microenvironment to leukemogenesis and leukemia progression.

Authors:  F Ayala; R Dewar; M Kieran; R Kalluri
Journal:  Leukemia       Date:  2009-09-03       Impact factor: 11.528

Review 10.  Hallmarks of cancer: the next generation.

Authors:  Douglas Hanahan; Robert A Weinberg
Journal:  Cell       Date:  2011-03-04       Impact factor: 41.582
View more
  13 in total

1.  Activity-dependent neuronal Klotho enhances astrocytic aerobic glycolysis.

Authors:  Caio H Mazucanti; Elisa M Kawamoto; Mark P Mattson; Cristoforo Scavone; Simonetta Camandola
Journal:  J Cereb Blood Flow Metab       Date:  2018-03-01       Impact factor: 6.200

2.  Targeting the leukemic bone marrow microenvironment.

Authors:  Eva Kristin von der Heide; Martin Neumann; Claudia D Baldus
Journal:  Oncotarget       Date:  2017-10-27

3.  Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway.

Authors:  Annalisa Lonetti; Alessandra Cappellini; Alice Bertaina; Franco Locatelli; Andrea Pession; Francesca Buontempo; Camilla Evangelisti; Cecilia Evangelisti; Ester Orsini; Laura Zambonin; Luca Maria Neri; Alberto Maria Martelli; Francesca Chiarini
Journal:  J Hematol Oncol       Date:  2016-10-24       Impact factor: 17.388

Review 4.  Biological Aspects of mTOR in Leukemia.

Authors:  Simone Mirabilii; Maria Rosaria Ricciardi; Monica Piedimonte; Valentina Gianfelici; Maria Paola Bianchi; Agostino Tafuri
Journal:  Int J Mol Sci       Date:  2018-08-14       Impact factor: 5.923

Review 5.  The Autophagy in Osteoimmonology: Self-Eating, Maintenance, and Beyond.

Authors:  Lan Xiao; Yin Xiao
Journal:  Front Endocrinol (Lausanne)       Date:  2019-07-23       Impact factor: 5.555

Review 6.  mTOR Regulation of Metabolism in Hematologic Malignancies.

Authors:  Simone Mirabilii; Maria Rosaria Ricciardi; Agostino Tafuri
Journal:  Cells       Date:  2020-02-11       Impact factor: 6.600

7.  Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL.

Authors:  Pierre-Yves Dumas; Cécile Naudin; Séverine Martin-Lannerée; Brigitte Izac; Luana Casetti; Olivier Mansier; Benoît Rousseau; Alexandre Artus; Mélody Dufossée; Alban Giese; Pierre Dubus; Arnaud Pigneux; Vincent Praloran; Audrey Bidet; Arnaud Villacreces; Amélie Guitart; Noël Milpied; Olivier Kosmider; Isabelle Vigon; Vanessa Desplat; Isabelle Dusanter-Fourt; Jean-Max Pasquet
Journal:  Haematologica       Date:  2019-03-28       Impact factor: 9.941

8.  CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.

Authors:  Toma A Yakulov; Abhijeet P Todkar; Krasimir Slanchev; Johannes Wiegel; Alexandra Bona; Martin Groß; Alexander Scholz; Isabell Hess; Anne Wurditsch; Florian Grahammer; Tobias B Huber; Virginie Lecaudey; Tillmann Bork; Jochen Hochrein; Melanie Boerries; Justine Leenders; Pascal de Tullio; François Jouret; Albrecht Kramer-Zucker; Gerd Walz
Journal:  Nat Commun       Date:  2018-09-10       Impact factor: 14.919

Review 9.  The Induction of a Permissive Environment to Promote T Cell Immune Evasion in Acute Myeloid Leukemia: The Metabolic Perspective.

Authors:  Dimitrios Mougiakakos
Journal:  Front Oncol       Date:  2019-11-06       Impact factor: 6.244

10.  Clinical and prognostic relevance of CXCL12 expression in acute myeloid leukemia.

Authors:  Shi-Sen Wang; Zi-Jun Xu; Ye Jin; Ji-Chun Ma; Pei-Hui Xia; Xiangmei Wen; Zhen-Wei Mao; Jiang Lin; Jun Qian
Journal:  PeerJ       Date:  2021-07-20       Impact factor: 2.984
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.