Literature DB >> 2695058

Two sequence-specific binding proteins from the promoter region of the c-Ha-ras-I oncogene.

T Dimitrov1.   

Abstract

The role of sequence-specific binding proteins in transcriptional control in higher eukaryotes is unclear. We have investigated the control region of the c-Ha-ras-I protooncogene containing upstream sequences from the transcriptional initiation point. Two proteins, which bind these sequences, with molecular weights of 20 K and 43 K were found. The possible role in the process of transformation is discussed.

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Year:  1989        PMID： 2695058     DOI： 10.1007/BF02399668

Source DB:  PubMed          Journal:  Biochem Genet        ISSN： 0006-2928            Impact factor:   1.890


  9 in total

1.  beta-Galactosidase chimeras: primary structure of a lac repressor-beta-galactosidase protein.

Authors:  A J Brake; A V Fowler; I Zabin; J Kania; B Müller-Hill
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

2.  Novel method for identifying sequence-specific DNA-binding proteins.

Authors:  D Levens; P M Howley
Journal:  Mol Cell Biol       Date:  1985-09       Impact factor: 4.272

3.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

4.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

5.  Purification and biochemical characterization of the promoter-specific transcription factor, Sp1.

Authors:  M R Briggs; J T Kadonaga; S P Bell; R Tjian
Journal:  Science       Date:  1986-10-03       Impact factor: 47.728

6.  The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter.

Authors:  W S Dynan; R Tjian
Journal:  Cell       Date:  1983-11       Impact factor: 41.582

7.  DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

Authors:  J L Manley; A Fire; A Cano; P A Sharp; M L Gefter
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

8.  High expression levels of ras p21 protein in normal mouse heart tissues.

Authors:  D A Spandidos; T Dimitrov
Journal:  Biosci Rep       Date:  1985-12       Impact factor: 3.840

9.  Elevated expression of the human ras oncogene family in premalignant and malignant tumours of the colorectum.

Authors:  D A Spandidos; I B Kerr
Journal:  Br J Cancer       Date:  1984-06       Impact factor: 7.640
  9 in total

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