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Literature DB >> 26949744

Intercellular conduits in tumours: the new social network.

Abstract

The role of intercellular communication is increasingly recognized as being critical to tumoral invasion, metastasis, and development of resistance to therapy. The recent discovery of cellular protrusions - tumour microtubes - connecting cancer cells in gliomas, and tunneling nanotubes in several other forms of cancer, sheds light on a novel mechanism for molecular networking. Interrupting and disrupting vital lines of intercellular cross-talk via these membranous cellular tubes has strong potential as a novel form of cancer-directed therapy.

Entities: Chemical Disease Gene Species

Keywords: brain tumor networks; cellular protrusions; glioblastoma; intercellular communication; tumour microtubes; tunneling nanotubes

Year: 2016 PMID： 26949744 PMCID： PMC4776333 DOI： 10.1016/j.trecan.2015.12.004

Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025

10 in total

1. Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels.

Authors: Xiang Wang; Margaret Lin Veruki; Nickolay V Bukoreshtliev; Espen Hartveit; Hans-Hermann Gerdes
Journal: Proc Natl Acad Sci U S A Date: 2010-09-20 Impact factor: 11.205

2. B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment.

Authors: Roel Polak; Bob de Rooij; Rob Pieters; Monique L den Boer
Journal: Blood Date: 2015-08-21 Impact factor: 22.113

3. Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes.

Authors: Venugopal Thayanithy; Elizabeth L Dickson; Clifford Steer; Subbaya Subramanian; Emil Lou
Journal: Transl Res Date: 2014-05-24 Impact factor: 7.012

4. Tumor exosomes induce tunneling nanotubes in lipid raft-enriched regions of human mesothelioma cells.

Authors: Venugopal Thayanithy; Victor Babatunde; Elizabeth L Dickson; Phillip Wong; Sanghoon Oh; Xu Ke; Afsar Barlas; Sho Fujisawa; Yevgeniy Romin; André L Moreira; Robert J Downey; Clifford J Steer; Subbaya Subramanian; Katia Manova-Todorova; Malcolm A S Moore; Emil Lou
Journal: Exp Cell Res Date: 2014-01-24 Impact factor: 3.905

Review 5. Targeting adaptive glioblastoma: an overview of proliferation and invasion.

Authors: Qian Xie; Sandeep Mittal; Michael E Berens
Journal: Neuro Oncol Date: 2014-07-30 Impact factor: 12.300

6. Brain tumour cells interconnect to a functional and resistant network.

Authors: Matthias Osswald; Erik Jung; Felix Sahm; Gergely Solecki; Varun Venkataramani; Jonas Blaes; Sophie Weil; Heinz Horstmann; Benedikt Wiestler; Mustafa Syed; Lulu Huang; Miriam Ratliff; Kianush Karimian Jazi; Felix T Kurz; Torsten Schmenger; Dieter Lemke; Miriam Gömmel; Martin Pauli; Yunxiang Liao; Peter Häring; Stefan Pusch; Verena Herl; Christian Steinhäuser; Damir Krunic; Mostafa Jarahian; Hrvoje Miletic; Anna S Berghoff; Oliver Griesbeck; Georgios Kalamakis; Olga Garaschuk; Matthias Preusser; Samuel Weiss; Haikun Liu; Sabine Heiland; Michael Platten; Peter E Huber; Thomas Kuner; Andreas von Deimling; Wolfgang Wick; Frank Winkler
Journal: Nature Date: 2015-11-04 Impact factor: 49.962

7. Tunneling nanotubes provide a unique conduit for intercellular transfer of cellular contents in human malignant pleural mesothelioma.

Authors: Emil Lou; Sho Fujisawa; Alexei Morozov; Afsar Barlas; Yevgeniy Romin; Yildirim Dogan; Sepideh Gholami; André L Moreira; Katia Manova-Todorova; Malcolm A S Moore
Journal: PLoS One Date: 2012-03-09 Impact factor: 3.240

8. Feedback within the inter-cellular communication and tumorigenesis in carcinomas.

Authors: Felix Rückert; Robert Grützmann; Christian Pilarsky
Journal: PLoS One Date: 2012-05-17 Impact factor: 3.240

9. Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance.

Authors: Jennifer Pasquier; Bella S Guerrouahen; Hamda Al Thawadi; Pegah Ghiabi; Mahtab Maleki; Nadine Abu-Kaoud; Arthur Jacob; Massoud Mirshahi; Ludovic Galas; Shahin Rafii; Frank Le Foll; Arash Rafii
Journal: J Transl Med Date: 2013-04-10 Impact factor: 5.531

10. Tumour exosome integrins determine organotropic metastasis.

Authors: Ayuko Hoshino; Bruno Costa-Silva; Tang-Long Shen; Goncalo Rodrigues; Ayako Hashimoto; Milica Tesic Mark; Henrik Molina; Shinji Kohsaka; Angela Di Giannatale; Sophia Ceder; Swarnima Singh; Caitlin Williams; Nadine Soplop; Kunihiro Uryu; Lindsay Pharmer; Tari King; Linda Bojmar; Alexander E Davies; Yonathan Ararso; Tuo Zhang; Haiying Zhang; Jonathan Hernandez; Joshua M Weiss; Vanessa D Dumont-Cole; Kimberly Kramer; Leonard H Wexler; Aru Narendran; Gary K Schwartz; John H Healey; Per Sandstrom; Knut Jørgen Labori; Elin H Kure; Paul M Grandgenett; Michael A Hollingsworth; Maria de Sousa; Sukhwinder Kaur; Maneesh Jain; Kavita Mallya; Surinder K Batra; William R Jarnagin; Mary S Brady; Oystein Fodstad; Volkmar Muller; Klaus Pantel; Andy J Minn; Mina J Bissell; Benjamin A Garcia; Yibin Kang; Vinagolu K Rajasekhar; Cyrus M Ghajar; Irina Matei; Hector Peinado; Jacqueline Bromberg; David Lyden
Journal: Nature Date: 2015-10-28 Impact factor: 49.962

10 in total

11 in total

1. The Art of War and oncology: applying the principles of strategy and tactics to greater effect in the era of targeted therapy.

Authors: Emil Lou
Journal: Ann Transl Med Date: 2018-05

2. Novel approaches for glioblastoma treatment: Focus on tumor heterogeneity, treatment resistance, and computational tools.

Authors: Silvana Valdebenito; Daniela D'Amico; Eliseo Eugenin
Journal: Cancer Rep (Hoboken) Date: 2019-11-11

Review 3. Lost in translation: applying 2D intercellular communication via tunneling nanotubes in cell culture to physiologically relevant 3D microenvironments.

Authors: Emil Lou; Patrick O'Hare; Subbaya Subramanian; Clifford J Steer
Journal: FEBS J Date: 2016-11-30 Impact factor: 5.542

4. Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes.

Authors: Elise Delage; Diégo Cordero Cervantes; Esthel Pénard; Christine Schmitt; Sylvie Syan; Andrea Disanza; Giorgio Scita; Chiara Zurzolo
Journal: Sci Rep Date: 2016-12-23 Impact factor: 4.379

5. The Role of Rho-GTPases and actin polymerization during Macrophage Tunneling Nanotube Biogenesis.

Authors: Samer J Hanna; Kessler McCoy-Simandle; Veronika Miskolci; Peng Guo; Michael Cammer; Louis Hodgson; Dianne Cox
Journal: Sci Rep Date: 2017-08-17 Impact factor: 4.379

6. Modeling membrane nanotube morphology: the role of heterogeneity in composition and material properties.

Authors: Haleh Alimohamadi; Ben Ovryn; Padmini Rangamani
Journal: Sci Rep Date: 2020-02-13 Impact factor: 4.379

Review 7. A Ticket to Ride: The Implications of Direct Intercellular Communication via Tunneling Nanotubes in Peritoneal and Other Invasive Malignancies.

Authors: Emil Lou
Journal: Front Oncol Date: 2020-11-26 Impact factor: 6.244

8. Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding.

Authors: Tone A Fykerud; Lars M Knudsen; Max Z Totland; Vigdis Sørensen; Shiva Dahal-Koirala; Ragnhild A Lothe; Andreas Brech; Edward Leithe
Journal: Cell Cycle Date: 2016-09-13 Impact factor: 4.534

Review 9. The Novel Roles of Connexin Channels and Tunneling Nanotubes in Cancer Pathogenesis.

Authors: Silvana Valdebenito; Emil Lou; John Baldoni; George Okafo; Eliseo Eugenin
Journal: Int J Mol Sci Date: 2018-04-24 Impact factor: 5.923

10. Tunneling nanotubes, TNT, communicate glioblastoma with surrounding non-tumor astrocytes to adapt them to hypoxic and metabolic tumor conditions.

Authors: Silvana Valdebenito; Shaily Malik; Ross Luu; Olivier Loudig; Megan Mitchell; George Okafo; Krishna Bhat; Brendan Prideaux; Eliseo A Eugenin
Journal: Sci Rep Date: 2021-07-15 Impact factor: 4.379