Literature DB >> 26945487

Pancreatic manifestations in von Hippel-Lindau disease: A case report.

Subhashini Ayloo1, Michele Molinari2.   

Abstract

INTRODUCTION: Pancreatic manifestations in Von Hippel-Lindau (VHL) disease can present as a multitude of forms, and their management can be challenging. PRESENTATION OF THE CASE: A 66-year-old woman presented with increasing abdominal girth without other associated symptoms of nausea, vomiting, abdominal pain, weight-loss, and jaundice. Her medical and surgical histories were significant for type II diabetes, cerebral tumor resection, bilateral nephrectomies, and laser photocoagulation of retinal hemangiomas. Computed tomography (CT) of the abdomen showed a massive multi-cystic lesion in the pancreas and the patient was referred to our hepatopancreatic biliary center. DISCUSSION: The findings on the subsequent cross-sectional MRI imaging signified pancreatic manifestations in VHL disease.
CONCLUSION: The management of VHL disease-associated benign pancreatic cystic lesions involves interval monitoring with cross-sectional imaging for malignant changes/development.
Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Entities:  

Keywords:  Case report; Pancreatic cyst; Pancreatic neuroendocrine tumor; Serous cystadenoma; Von Hippel–Lindau disease

Year:  2016        PMID: 26945487      PMCID: PMC4802197          DOI: 10.1016/j.ijscr.2016.02.031

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  11 in total

1.  von Hippel-Lindau disease-associated solid microcystic serous adenomas masquerading as pancreatic neuroendocrine neoplasms.

Authors:  Simon Turcotte; Baris Turkbey; Stephanie Barak; Steven K Libutti; H Richard Alexander; W Marston Linehan; Marybeth S Hughes; Naris Nilubol; Krisana Gesuwan; Corina Millo; Martha Quezado; Peter L Choyke; Electron Kebebew; Giao Q Phan
Journal:  Surgery       Date:  2012-10-27       Impact factor: 3.982

Review 2.  Pancreatic lesions in von Hippel-Lindau disease? A systematic review and meta-synthesis of the literature.

Authors:  Michael Charlesworth; Caroline S Verbeke; Gavin A Falk; Matthew Walsh; Andrew M Smith; Gareth Morris-Stiff
Journal:  J Gastrointest Surg       Date:  2012-02-28       Impact factor: 3.452

Review 3.  Spectrum of magnetic resonance imaging findings in pancreatic and other abdominal manifestations of Von Hippel-Lindau disease in a series of 23 patients: a pictorial review.

Authors:  Rossella Graziani; Simona Mautone; Mario Vigo; Riccardo Manfredi; Giuseppe Opocher; Massimo Falconi
Journal:  JOP       Date:  2014-01-10

Review 4.  Pancreatic involvement in von Hippel-Lindau disease: report of two cases and review of the literature.

Authors:  Luca Elli; Elisabetta Buscarini; Vanessa Portugalli; Luigi Reduzzi; Chiara Reduzzi; Gianfranco Brambilla; Fernanda Menozzi; Maria Teresa Bardella; Luca P Piodi; Maja Caldato; Alessandro Zambelli
Journal:  Am J Gastroenterol       Date:  2006-09-04       Impact factor: 10.864

5.  Diagnosis and management of pancreatic neuroendocrine tumor in von Hippel-Lindau disease.

Authors:  Kenji Tamura; Isao Nishimori; Tetsuhide Ito; Ichiro Yamasaki; Hisato Igarashi; Taro Shuin
Journal:  World J Gastroenterol       Date:  2010-09-28       Impact factor: 5.742

6.  Abdominal visceral lesions in von Hippel-Lindau disease: incidence and clinical behavior of pancreatic and adrenal lesions at a single center.

Authors:  Keith A Delman; Suzanne E Shapiro; Eric W Jonasch; Jeffrey E Lee; Steven A Curley; Douglas B Evans; Nancy D Perrier
Journal:  World J Surg       Date:  2006-05       Impact factor: 3.352

7.  Von Hippel Lindau disease [VHL]: magnetic resonance imaging spectrum in a single patient.

Authors:  Sandeep G Jakhere; Bhakti Yeragi; Darshan G Jain
Journal:  Acta Med Indones       Date:  2012-10

8.  Clinical, genetic and radiographic analysis of 108 patients with von Hippel-Lindau disease (VHL) manifested by pancreatic neuroendocrine neoplasms (PNETs).

Authors:  Joseph A Blansfield; Lynda Choyke; Shane Y Morita; Peter L Choyke; James F Pingpank; H Richard Alexander; Geoffrey Seidel; Yvonne Shutack; Nargiza Yuldasheva; Michelle Eugeni; David L Bartlett; Gladys M Glenn; Lindsay Middelton; W Marston Linehan; Steven K Libutti
Journal:  Surgery       Date:  2007-12       Impact factor: 3.982

9.  Neuroendocrine tumor of the pancreas and bilateral adrenal pheochromocytomas. A rare manifestation of von Hippel-Lindau disease in childhood.

Authors:  Jan M Langrehr; Marcus Bahra; Glen Kristiansen; Hartmut P H Neumann; Luitgard M Neumann; Ursula Plöckinger; Enrique Lopez-Hänninen
Journal:  J Pediatr Surg       Date:  2007-07       Impact factor: 2.545

10.  Pancreatic involvement in Korean patients with von Hippel-Lindau disease.

Authors:  Kwang Hyuck Lee; Jae Seung Lee; Bum Jin Kim; Jong Kyun Lee; Seong Hyun Kim; Seung Hoon Kim; Kyu Taek Lee
Journal:  J Gastroenterol       Date:  2009-03-31       Impact factor: 7.527

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  1 in total

1.  Von Hippel-Lindau Disease With Multi-Organ Involvement: A Case Report and 8-Year Clinical Course With Follow-Up.

Authors:  Ali Yaghobi Joybari; Payam Azadeh
Journal:  Am J Case Rep       Date:  2017-11-17
  1 in total

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