| Literature DB >> 26944613 |
Ke Wang1, Frédéric Friscourt2, Chaofeng Dai1, Lifang Wang1, Yueqin Zheng1, Geert-Jan Boons2, Siming Wang1, Binghe Wang3.
Abstract
Sodium azide is toxic and widely used in agricultural, commercial products, and research laboratories. Thus it is of a significant environmental concern and there is a need for the development of a rapid detection method. A fluorogenic dibenzylcyclooctyne derivative (Fl-DIBO) is herein described as a fluorescent probe for the rapid detection of inorganic azide via Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC). Fl-DIBO was found to be highly selective toward NaN3 in comparison to other common anions with good sensitivity and detection limit of 10μM. Published by Elsevier Ltd.Entities:
Keywords: Click chemistry; Fluorescent detection; Quantitative analysis; Sodium azide
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Year: 2016 PMID: 26944613 PMCID: PMC4797929 DOI: 10.1016/j.bmcl.2016.02.069
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823