| Literature DB >> 26940946 |
Abstract
In this paper, a mathematical model is proposed and analyzed for Hepatitis C virus (HCV) infection transmissions. In this model, both of chronic primary infection and possibility of reinfection are considered. Two thresholds of basic reproduction number R0 and control reproduction number Rc are derived. We get the sufficient conditions for the existence of infection-free equilibrium and endemic equilibrium. The sufficient conditions for the local and global stability of the equilibria are also obtained. Some numerical simulations are performed to prove the theoretical results. At last, some discussions are presented.Entities:
Keywords: Basic reproduction number; Control reproduction number; Endemic equilibrium; Hepatitis C virus (HCV); Infection-free equilibrium; Reinfection; Stability
Mesh:
Year: 2016 PMID: 26940946 DOI: 10.1016/j.virusres.2016.02.006
Source DB: PubMed Journal: Virus Res ISSN: 0168-1702 Impact factor: 3.303