Literature DB >> 26940520

Membrane Trafficking in Neuronal Development: Ins and Outs of Neural Connectivity.

Cortney Chelise Winkle1, Stephanie L Gupton2.   

Abstract

During development, neurons progress through rapid yet stereotypical shape changes to achieve proper neuronal connectivity. This morphological progression requires carefully orchestrated plasma membrane expansion, insertion of membrane components including receptors for extracellular cues into the plasma membrane and removal and trafficking of membrane materials and proteins to specific locations. This review outlines the cellular machinery of membrane trafficking that play an integral role in neuronal cell shape change and function from initial neurite formation to pathway navigation and synaptogenesis.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Golgi apparatus; Golgi outposts; endocytosis; endoplasmic reticulum; exocytosis; membrane trafficking; neuron; neuronal development

Mesh:

Year:  2016        PMID: 26940520      PMCID: PMC4797321          DOI: 10.1016/bs.ircmb.2015.10.003

Source DB:  PubMed          Journal:  Int Rev Cell Mol Biol        ISSN: 1937-6448            Impact factor:   6.813


  155 in total

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