Literature DB >> 26939744

From mutated genes to familial Alzheimer's disease.

Tziona Ben-Gedalya1,2, Ehud Cohen1.   

Abstract

Entities:  

Keywords:  alzheimer's disease; amyloid β; neurodegeneration; presenilin 1; γ secretase

Mesh：

Year:  2016        PMID： 26939744      PMCID： PMC4889310          DOI： 10.1080/15384101.2016.1151727

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Novel research horizons for presenilins and γ-secretases in cell biology and disease.

Authors:  Bart De Strooper; Wim Annaert
Journal:  Annu Rev Cell Dev Biol       Date:  2010       Impact factor: 13.827

Review 2.  Alzheimer's disease: the amyloid cascade hypothesis.

Authors:  J A Hardy; G A Higgins
Journal:  Science       Date:  1992-04-10       Impact factor: 47.728

3.  The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.

Authors:  J Kang; H G Lemaire; A Unterbeck; J M Salbaum; C L Masters; K H Grzeschik; G Multhaup; K Beyreuther; B Müller-Hill
Journal:  Nature       Date:  1987 Feb 19-25       Impact factor: 49.962

4.  Alzheimer's disease-causing proline substitutions lead to presenilin 1 aggregation and malfunction.

Authors:  Tziona Ben-Gedalya; Lorna Moll; Michal Bejerano-Sagie; Samuel Frere; Wayne A Cabral; Dinorah Friedmann-Morvinski; Inna Slutsky; Tal Burstyn-Cohen; Joan C Marini; Ehud Cohen
Journal:  EMBO J       Date:  2015-10-05       Impact factor: 11.598

5.  Amyloid plaque core protein in Alzheimer disease and Down syndrome.

Authors:  C L Masters; G Simms; N A Weinman; G Multhaup; B L McDonald; K Beyreuther
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

6.  Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease.

Authors:  Dan Xia; Hirotaka Watanabe; Bei Wu; Sang Hun Lee; Yan Li; Evgeny Tsvetkov; Vadim Y Bolshakov; Jie Shen; Raymond J Kelleher
Journal:  Neuron       Date:  2015-03-04       Impact factor: 17.173

7.  Qualitative changes in human γ-secretase underlie familial Alzheimer's disease.

Authors:  Maria Szaruga; Sarah Veugelen; Manasi Benurwar; Sam Lismont; Diego Sepulveda-Falla; Alberto Lleo; Natalie S Ryan; Tammaryn Lashley; Nick C Fox; Shigeo Murayama; Harrie Gijsen; Bart De Strooper; Lucía Chávez-Gutiérrez
Journal:  J Exp Med       Date:  2015-10-19       Impact factor: 14.307
  7 in total

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