Literature DB >> 26938147

Visible Light and pH Responsive Polymer-Coated Mesoporous Silica Nanohybrids for Controlled Release.

Guojie Wang1, Jie Dong1, Tingting Yuan1, Juchen Zhang2, Lei Wang2, Hao Wang2.   

Abstract

A visible light and pH responsive anticancer drug delivery system based on polymer-coated mesoporous silica nanoparticles (MSNs) has been developed. Perylene-functionalized poly(dimethylaminoethyl methacrylates) sensitive to visible light and pH are electrostatically attached on the surface of MSNs to seal the nanopores. Stimulation of visible light and acid can unseal the nanopores to induce controlled drug release from the MSNs. More interestingly, the release can be enhanced under the combined stimulation of the dual-stimuli. The synergistic effect of visible light and acid stimulation on the efficient release of anticancer drugs from the nanohybrids endows the system with great potential for cancer therapy.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  nanocomposites; self-assembly; stimuli-sensitive polymers; thin films

Mesh：

Substances：

Year:  2016        PMID： 26938147     DOI： 10.1002/mabi.201600008

Source DB:  PubMed          Journal:  Macromol Biosci        ISSN： 1616-5187            Impact factor:   4.979


  7 in total

1.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

Review 2.  Functionalization of Nanoparticulate Drug Delivery Systems and Its Influence in Cancer Therapy.

Authors:  Theodora Amanda Seidu; Perpetua Takunda Kutoka; Dorothy Owusu Asante; Muhammad Asim Farooq; Raphael N Alolga; Wang Bo
Journal:  Pharmaceutics       Date:  2022-05-23       Impact factor: 6.525

Review 3.  Advances in mesoporous silica nanoparticles for targeted stimuli-responsive drug delivery: an update.

Authors:  Rafael R Castillo; Daniel Lozano; Blanca González; Miguel Manzano; Isabel Izquierdo-Barba; María Vallet-Regí
Journal:  Expert Opin Drug Deliv       Date:  2019-04-22       Impact factor: 6.648

4.  Visible-light-triggered supramolecular valves based on β-cyclodextrin-modified mesoporous silica nanoparticles for controlled drug release.

Authors:  Qing Bian; Zhaolu Xue; Po Sun; Kejing Shen; Shangbing Wang; Juanying Jia
Journal:  RSC Adv       Date:  2019-06-03       Impact factor: 4.036

Review 5.  Polymer-Based Hybrid Nanoarchitectures for Cancer Therapy Applications.

Authors:  Arun Kumar; Mirkomil Sharipov; Abbaskhan Turaev; Shavkatjon Azizov; Ismatdjan Azizov; Edwin Makhado; Abbas Rahdar; Deepak Kumar; Sadanand Pandey
Journal:  Polymers (Basel)       Date:  2022-07-26       Impact factor: 4.967

Review 6.  Physically stimulus-responsive nanoparticles for therapy and diagnosis.

Authors:  Fatemeh Farjadian; Soheila Ghasemi; Mohsen Akbarian; Mojtaba Hoseini-Ghahfarokhi; Mohsen Moghoofei; Mohammad Doroudian
Journal:  Front Chem       Date:  2022-09-14       Impact factor: 5.545

Review 7.  Influence of the Surface Functionalization on the Fate and Performance of Mesoporous Silica Nanoparticles.

Authors:  Miguel Gisbert-Garzarán; María Vallet-Regí
Journal:  Nanomaterials (Basel)       Date:  2020-05-09       Impact factor: 5.076
  7 in total

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