Literature DB >> 26936363

[Nystagmus. Clinical characteristics and therapeutic options].

B Käsmann-Kellner1.   

Abstract

This article presents an overview of the pathophysiology of nystagmus and the differential diagnostics of congenital and acquired nystagmus. In addition, the principles of conservative, surgical and pharmacotherapy treatment options are described. The pathophysiological basis of nystagmus deepens the understanding of the etiology of the individual forms of nystagmus. The therapeutic approach to calming of nystagmus aims at an extension of the foveation time, which has the most significant impact on visual acuity. In congenital nystagmus this can be carried out by optimization of the retinal image, prisms or by bilateral surgical muscle repositioning to use the phenomenon of a null or neutral zone. In acquired nystagmus the off-label use of centrally acting medications can sometimes be helpful to calm the nystagmus and the associated oscillopsia.

Entities:  

Keywords:  Acquired nystagmus; Congenital nystagmus; Drugs; Infantile nystagmus syndrome; Pathophysiology

Mesh:

Substances:

Year:  2016        PMID: 26936363     DOI: 10.1007/s00347-016-0225-9

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  6 in total

1.  Horizontal rectus muscle tenotomy in children with infantile nystagmus syndrome: a pilot study.

Authors:  Richard W Hertle; Louis F Dell'Osso; Edmond J FitzGibbon; Dongsheng Yang; Susan D Mellow
Journal:  J AAPOS       Date:  2004-12       Impact factor: 1.220

2.  Congenital nystagmus: randomized, controlled, double-masked trial of memantine/gabapentin.

Authors:  Rebecca McLean; Frank Proudlock; Shery Thomas; Chris Degg; Irene Gottlob
Journal:  Ann Neurol       Date:  2007-02       Impact factor: 10.422

3.  Surgery for nystagmus related head turn: Kestenbaum procedure and artificial divergence.

Authors:  M Gräf; K Droutsas; H Kaufmann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2001-06       Impact factor: 3.117

Review 4.  Development of new treatments for congenital nystagmus.

Authors:  Louis F Dell'Osso
Journal:  Ann N Y Acad Sci       Date:  2002-04       Impact factor: 5.691

Review 5.  Nystagmus in infancy and childhood: characteristics and evidence for treatment.

Authors:  Richard W Hertle
Journal:  Am Orthopt J       Date:  2010

6.  Fusion maldevelopment (latent/manifest latent) nystagmus syndrome: effects of four-muscle tenotomy and reattachment.

Authors:  Louis F Dell'Osso; Faruk H Orge; Jonathan B Jacobs; Zhong I Wang
Journal:  J Pediatr Ophthalmol Strabismus       Date:  2014-04-02       Impact factor: 1.402

  6 in total

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