Literature DB >> 26936155

Bioactive Secondary Metabolites with Unique Aromatic and Heterocyclic Structures Obtained from Terrestrial Actinomycetes Species.

Mohamed S Abdelfattah1, Midori A Arai, Masami Ishibashi.   

Abstract

Natural products from actinomycetes are important and valuable sources for drug discovery and the development of biological tools. The present review describes our recent study on the isolation of new natural products mainly possessing heterocyclic and aromatic ring structures with biological effects on cancer-related cellular pathways such as tumor necrosis factor-α-related apoptosis-inducing ligand (TRAIL) and Wnt signaling.

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Year:  2016        PMID： 26936155     DOI： 10.1248/cpb.c16-00038

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  3 in total

1.  Sharkquinone, a new ana-quinonoid tetracene derivative from marine-derived Streptomyces sp. EGY1 with TRAIL resistance-overcoming activity.

Authors:  Mohamed S Abdelfattah; Mohammed I Y Elmallah; Adal A Mohamed; Masami Ishibashi
Journal:  J Nat Med       Date:  2017-04-04       Impact factor: 2.343

Review 2.  Small Molecule Wnt Pathway Modulators from Natural Sources: History, State of the Art and Perspectives.

Authors:  Artem Blagodatski; Antonina Klimenko; Lee Jia; Vladimir L Katanaev
Journal:  Cells       Date:  2020-03-02       Impact factor: 6.600

Review 3.  Secondary Metabolites of Actinomycetes and their Antibacterial, Antifungal and Antiviral Properties.

Authors:  Katarzyna Jakubiec-Krzesniak; Aleksandra Rajnisz-Mateusiak; Adam Guspiel; Joanna Ziemska; Jolanta Solecka
Journal:  Pol J Microbiol       Date:  2018
  3 in total

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