Literature DB >> 26936100

Highlights of the 8th International Conference on Vaccines for Enteric Diseases: the Scottish Encounter To Defeat Diarrheal Diseases.

Sharon M Tennant1, A Duncan Steele2, Marcela F Pasetti3.   

Abstract

Infectious diarrhea is a leading cause of morbidity and of mortality; the burden of disease affects individuals of all ages but particularly young children, especially those living in poor regions where the disease is endemic. It is also a health concern for international travelers to these areas. Experts on vaccines and enteric infections and advocates for global health improvement gathered in Scotland from 8 to 10 July 2015 to discuss recent advances in the assessment and understanding of the burden of enteric diseases and progress in the development and implementation of strategies to prevent these infections. Highlights of the meeting included description of advances in molecular assays to estimate pathogen-specific prevalence, methods to model epidemiologic trends, novel approaches to generate broad-spectrum vaccines, new initiatives to evaluate vaccine performance where they are most needed, renewed interest in human challenge models, immunological readouts as predictors of vaccine efficacy, maternal immunization to prevent enteric infections, and the impact of maternal immunity on the vaccine take of infants. A follow-up scientific gathering to advance Shigella and enterotoxigenic Escherichia coli (ETEC) vaccine efforts will be held from 28 to 30 June 2016 in Washington, DC.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID: 26936100      PMCID: PMC4820512          DOI: 10.1128/CVI.00082-16

Source DB:  PubMed          Journal:  Clin Vaccine Immunol        ISSN: 1556-679X


  37 in total

1.  A combination vaccine consisting of three live attenuated enterotoxigenic Escherichia coli strains expressing a range of colonization factors and heat-labile toxin subunit B is well tolerated and immunogenic in a placebo-controlled double-blind phase I trial in healthy adults.

Authors:  Clayton Harro; David Sack; A Louis Bourgeois; R Walker; Barbara DeNearing; Andrea Feller; Subhra Chakraborty; Charlotte Buchwaldt; Michael J Darsley
Journal:  Clin Vaccine Immunol       Date:  2011-10-12

2.  Rapid effects of a protective O-polysaccharide-specific monoclonal IgA on Vibrio cholerae agglutination, motility, and surface morphology.

Authors:  Kara J Levinson; Magdia De Jesus; Nicholas J Mantis
Journal:  Infect Immun       Date:  2015-02-09       Impact factor: 3.441

3.  Rotavirus vaccines:an update.

Authors: 
Journal:  Wkly Epidemiol Rec       Date:  2009-12-18

4.  Etiology of childhood diarrhea after rotavirus vaccine introduction: a prospective, population-based study in Nicaragua.

Authors:  Sylvia Becker-Dreps; Filemon Bucardo; Samuel Vilchez; Luis Enrique Zambrana; Lan Liu; David J Weber; Rodolfo Peña; Leslie Barclay; Jan Vinjé; Michael G Hudgens; Johan Nordgren; Lennart Svensson; Douglas R Morgan; Félix Espinoza; Margarita Paniagua
Journal:  Pediatr Infect Dis J       Date:  2014-11       Impact factor: 2.129

5.  Refinement of a human challenge model for evaluation of enterotoxigenic Escherichia coli vaccines.

Authors:  Clayton Harro; Subhra Chakraborty; Andrea Feller; Barbara DeNearing; Alicia Cage; Malathi Ram; Anna Lundgren; Ann-Mari Svennerholm; August L Bourgeois; Richard I Walker; David A Sack
Journal:  Clin Vaccine Immunol       Date:  2011-08-18

6.  Antibiotic-free plasmid stabilization by operator-repressor titration for vaccine delivery by using live Salmonella enterica Serovar typhimurium.

Authors:  Helen S Garmory; Matthew W Leckenby; Kate F Griffin; Stephen J Elvin; Rosa R Taylor; M Gill Hartley; Julian A J Hanak; E Diane Williamson; Rocky M Cranenburgh
Journal:  Infect Immun       Date:  2005-04       Impact factor: 3.441

7.  Norovirus vaccine against experimental human GII.4 virus illness: a challenge study in healthy adults.

Authors:  David I Bernstein; Robert L Atmar; G Marshall Lyon; John J Treanor; Wilbur H Chen; Xi Jiang; Jan Vinjé; Nicole Gregoricus; Robert W Frenck; Christine L Moe; Mohamed S Al-Ibrahim; Jill Barrett; Jennifer Ferreira; Mary K Estes; David Y Graham; Robert Goodwin; Astrid Borkowski; Ralf Clemens; Paul M Mendelman
Journal:  J Infect Dis       Date:  2014-09-09       Impact factor: 5.226

8.  Interference of Monovalent, Bivalent, and Trivalent Oral Poliovirus Vaccines on Monovalent Rotavirus Vaccine Immunogenicity in Rural Bangladesh.

Authors:  Devy M Emperador; Daniel E Velasquez; Concepcion F Estivariz; Ben Lopman; Baoming Jiang; Umesh Parashar; Abhijeet Anand; Khalequ Zaman
Journal:  Clin Infect Dis       Date:  2015-09-08       Impact factor: 9.079

9.  The MAL-ED study: a multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical growth, cognitive development, and immune responses in infants and children up to 2 years of age in resource-poor environments.

Authors: 
Journal:  Clin Infect Dis       Date:  2014-11-01       Impact factor: 9.079

10.  Safety and immunogenicity of an improved oral inactivated multivalent enterotoxigenic Escherichia coli (ETEC) vaccine administered alone and together with dmLT adjuvant in a double-blind, randomized, placebo-controlled Phase I study.

Authors:  Anna Lundgren; Louis Bourgeois; Nils Carlin; John Clements; Björn Gustafsson; Marianne Hartford; Jan Holmgren; Max Petzold; Richard Walker; Ann-Mari Svennerholm
Journal:  Vaccine       Date:  2014-11-05       Impact factor: 3.641

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  4 in total

Review 1.  Childhood diarrhoeal diseases in developing countries.

Authors:  Harriet U Ugboko; Obinna C Nwinyi; Solomon U Oranusi; John O Oyewale
Journal:  Heliyon       Date:  2020-04-13

2.  Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study.

Authors:  Mark S Riddle; Robert W Kaminski; Claudio Di Paolo; Chad K Porter; Ramiro L Gutierrez; Kristen A Clarkson; Hailey E Weerts; Christopher Duplessis; Amy Castellano; Cristina Alaimo; Kristopher Paolino; Robert Gormley; Veronica Gambillara Fonck
Journal:  Clin Vaccine Immunol       Date:  2016-12-05

3.  Characterization of ShigETEC, a Novel Live Attenuated Combined Vaccine against Shigellae and ETEC.

Authors:  Shushan Harutyunyan; Irene Neuhauser; Alexandra Mayer; Michael Aichinger; Valéria Szijártó; Gábor Nagy; Eszter Nagy; Petra Girardi; Frank J Malinoski; Tamás Henics
Journal:  Vaccines (Basel)       Date:  2020-11-16

Review 4.  The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT.

Authors:  John D Clements; Elizabeth B Norton
Journal:  mSphere       Date:  2018-07-25       Impact factor: 4.389

  4 in total

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