Literature DB >> 26933969

Dissecting a Hub for Immune Response: Modeling the Structure of MyD88.

Chiara Naro1, Claudio Sette2.   

Abstract

Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.
Copyright © 2016 Elsevier Ltd. All rights reserved.

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Year:  2016        PMID: 26933969     DOI: 10.1016/j.str.2016.02.005

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  2 in total

1.  Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling.

Authors:  Mark M Hughes; Peter Lavrencic; Rebecca C Coll; Thomas Ve; Dylan G Ryan; Niamh C Williams; Deepthi Menon; Ashley Mansell; Philip G Board; Mehdi Mobli; Bostjan Kobe; Luke A J O'Neill
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-24       Impact factor: 11.205

2.  Spatiotemporal expression of MYD88 gene in pigs from birth to adulthood.

Authors:  LiNa Gan; WeiYun Qin; Sen Wu; ShengLong Wu; WenBin Bao
Journal:  Genet Mol Biol       Date:  2018-01-22       Impact factor: 1.771

  2 in total

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