Gustavo A Santa Cruz1. 1. Departamento Coordinación BNCT, Comisión Nacional de Energía Atómica (CNEA), Argentina.
Abstract
AIM: to present the most important aspects of Microdosimetry, a research field in radiation biophysics. BACKGROUND: microdosimetry is the branch of radiation biophysics that systematically studies the spatial, temporal and spectral aspects of the stochastic nature of the energy deposition processes in microscopic structures. MATERIALS AND METHODS: we briefly review its history, the people, the formalism and the theories and devices that allowed researchers to begin to understand the true nature of radiation action on living matter. RESULTS AND CONCLUSIONS: we outline some of its applications, especially to Boron Neutron Capture Therapy, attempting to explain the biological effectiveness of the boron thermal neutron capture reaction.
AIM: to present the most important aspects of Microdosimetry, a research field in radiation biophysics. BACKGROUND: microdosimetry is the branch of radiation biophysics that systematically studies the spatial, temporal and spectral aspects of the stochastic nature of the energy deposition processes in microscopic structures. MATERIALS AND METHODS: we briefly review its history, the people, the formalism and the theories and devices that allowed researchers to begin to understand the true nature of radiation action on living matter. RESULTS AND CONCLUSIONS: we outline some of its applications, especially to Boron Neutron Capture Therapy, attempting to explain the biological effectiveness of the boron thermal neutron capture reaction.