Literature DB >> 26933315

Inflammatory myofibroblastic tumor of the lung in pregnancy mimicking carcinoid tumor.

Venkata Nagarjuna Maturu1, Amanjit Bal2, Navneet Singh1.   

Abstract

Inflammatory myofibroblastic tumors (IMT) are uncommon neoplasms of the lung in adults. They constitute less than 1% of all lung neoplasms and usually present as parenchymal masses. Diagnosis requires a high index of suspicion. They are characterized by spindle-shaped tumor cells (fibroblasts/myofibroblasts) in a background of lymphoplasmacytic infiltrate. About 50% of the tumors harbor an ALK gene rearrangement. They have to be differentiated from inflammatory pseudotumors (IPT), which show increased number of IgG4 plasma cells on immunostaining and are negative for anaplastic lymphoma kinase (ALK) protein. Herein, we present a case of a 28-year old female who presented with hemoptysis and was diagnosed with an IMT of lung in the first trimester of pregnancy. We have not only reviewed the occurrence of IMT during pregnancy but also discuss the management options for IMT during pregnancy.

Entities:  

Keywords:  Carcinoid; inflammatory myofibroblastic tumor; lung tumor; pregnancy; surgical resection

Year:  2016        PMID: 26933315      PMCID: PMC4748673          DOI: 10.4103/0970-2113.173058

Source DB:  PubMed          Journal:  Lung India        ISSN: 0970-2113


  13 in total

Review 1.  Anaplastic lymphoma kinase-directed therapy in inflammatory myofibroblastic tumors.

Authors:  Zuzana Tothova; Andrew J Wagner
Journal:  Curr Opin Oncol       Date:  2012-07       Impact factor: 3.645

Review 2.  Inflammatory pseudotumor.

Authors:  Lakshmana Das Narla; Beverley Newman; Stephanie S Spottswood; Shireesha Narla; Rajasekhar Kolli
Journal:  Radiographics       Date:  2003 May-Jun       Impact factor: 5.333

3.  Bilateral simultaneous inflammatory myofibroblastic tumor of the lung with distant metastatic spread.

Authors:  Carolina Carillo; Marco Anile; Tiziano De Giacomo; Federico Venuta
Journal:  Interact Cardiovasc Thorac Surg       Date:  2011-05-22

4.  Inflammatory myofibroblastic tumor presenting with tracheal obstruction in a pregnant woman.

Authors:  Roy Amir; Daniel Danahey; Karen Ferrer; Mahmoud Maffee
Journal:  Am J Otolaryngol       Date:  2002 Nov-Dec       Impact factor: 1.808

5.  Inflammatory pseudotumor of the lung in adults.

Authors:  Giulio Melloni; Angelo Carretta; Paola Ciriaco; Gianluigi Arrigoni; Stefano Fieschi; Nathalie Rizzo; Edgardo Bonacina; Giuseppe Augello; Pier Angelo Belloni; Piero Zannini
Journal:  Ann Thorac Surg       Date:  2005-02       Impact factor: 4.330

Review 6.  Adult inflammatory myofibroblastic tumor of the trachea: case report and literature review.

Authors:  Funda Oztuna; Mehtap Pehlivanlar; Yasin Abul; Celal Tekinbas; Yavuz Ozoran; Tevfik Ozlu
Journal:  Respir Care       Date:  2012-12-18       Impact factor: 2.258

7.  Pulmonary inflammatory myofibroblastic tumor and IgG4-related inflammatory pseudotumor: a diagnostic dilemma.

Authors:  Priyanka Bhagat; Amanjit Bal; Ashim Das; Navneet Singh; Harkant Singh
Journal:  Virchows Arch       Date:  2013-10-08       Impact factor: 4.064

8.  Invasive inflammatory myofibroblastic tumor of the lung.

Authors:  Daniel A van den Heuvel; Ruth G Keijsers; Hendrik W van Es; Gerben P Bootsma; Peter C de Bruin; Franz M Schramel; Johannes P van Heesewijk
Journal:  J Thorac Oncol       Date:  2009-07       Impact factor: 15.609

9.  Complete remission of ALK-negative plasma cell granuloma (inflammatory myofibroblastic tumor) of the lung induced by celecoxib: A case report and review of the literature.

Authors:  Cinderella Chavez; Mark A Hoffman
Journal:  Oncol Lett       Date:  2013-03-15       Impact factor: 2.967

10.  Bronchoscopic resection of endobronchial inflammatory myofibroblastic tumor: A case report and systematic review of the literature.

Authors:  Animesh Ray; J C Suri; Dipak Bhattacharya; Ayush Gupta
Journal:  Lung India       Date:  2014-04
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  2 in total

1.  Transtracheal endoscopic-assisted resection of a rare inflammatory myofibroblastic tumour in adult trachea: a case report.

Authors:  S Reddy; R Swamy; D V Kumar Irugu; K V V Ramji
Journal:  Acta Otorhinolaryngol Ital       Date:  2018-04       Impact factor: 2.124

2.  Near-complete response to low-dose ceritinib in recurrent infantile inflammatory myofibroblastic tumour.

Authors:  Abhenil Mittal; Aarushi Gupta; Sameer Rastogi; Adarsh Barwad; Swati Sharma
Journal:  Ecancermedicalscience       Date:  2021-04-01
  2 in total

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