Literature DB >> 26932341

Patients with Psoriatic Arthritis Fulfilling the Minimal Disease Activity Criteria Do Not Have Swollen and Tender Joints, but Have Active Skin.

Josefina Marin1, María Laura Acosta Felquer1, Leandro Ferreyra Garrot1, Santiago Ruta1, Javier Rosa1, Enrique R Soriano2.   

Abstract

OBJECTIVE: To evaluate components of the minimal disease activity (MDA) criteria in psoriatic arthritis (PsA).
METHODS: In patients achieving and not achieving MDA, fulfillment of each of the 7 criteria was evaluated.
RESULTS: Among 41 patients with MDA, 7.4% did not fulfill the tender/swollen joint count whereas 49% did not fulfill the skin criteria. Of the 42 patients not fulfilling MDA, 100%, 76.5%, and 65% did not fulfill the patient pain score, the patient's global assessment, and the Psoriasis Area and Severity Index (PASI), respectively.
CONCLUSION: A minority of patients with PsA fulfilling the MDA criteria presented active joints, but half had active skin. Visual analog scale scores and the PASI prevented patients from achieving MDA.

Entities:  

Keywords:  MINIMAL DISEASE ACTIVITY; OUTCOME MEASURES; PSORIATIC ARTHRITIS; REMISSION

Mesh:

Year:  2016        PMID: 26932341     DOI: 10.3899/jrheum.151101

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  7 in total

1.  A 2-year observational study on treatment targets in psoriatic arthritis patients treated with TNF inhibitors.

Authors:  Maria Sole Chimenti; Paola Triggianese; Paola Conigliaro; Marco Tonelli; Gianfranco Gigliucci; Lucia Novelli; Miriam Teoli; Roberto Perricone
Journal:  Clin Rheumatol       Date:  2017-07-31       Impact factor: 2.980

2.  Residual symptoms and disease burden among patients with psoriatic arthritis: is a new disease activity index required?

Authors:  Gamze Kilic; Erkan Kilic; Kemal Nas; Ayhan Kamanlı; İbrahim Tekeoglu
Journal:  Rheumatol Int       Date:  2018-11-13       Impact factor: 2.631

3.  Psoriatic arthritis: is it time to treat-to-target or target to treat?

Authors:  Ennio Lubrano; Fabio Massimo Perrotta
Journal:  Clin Rheumatol       Date:  2017-10-24       Impact factor: 2.980

Review 4.  Residual Disease Associated with Suboptimal Treatment Response in Patients with Psoriatic Arthritis: A Systematic Review of Real-World Evidence.

Authors:  Laura C Coates; Maarten de Wit; Amy Buchanan-Hughes; Maartje Smulders; Anna Sheahan; Alexis R Ogdie
Journal:  Rheumatol Ther       Date:  2022-04-12

5.  Prediction and benefits of minimal disease activity in patients with psoriatic arthritis and active skin disease in the ADEPT trial.

Authors:  Philip J Mease; Arthur Kavanaugh; Laura C Coates; Iain B McInnes; Maja Hojnik; Ying Zhang; Jaclyn K Anderson; Alexander P Dorr; Dafna D Gladman
Journal:  RMD Open       Date:  2017-07-18

6.  Residual Disease in Patients with Axial Spondyloarthritis: A Post-Hoc Analysis of the QUASAR Study.

Authors:  Salvatore D'Angelo; Carlo Salvarani; Francesca Marando; Giuliana Gualberti; Lucia Novelli; Giacomo Curradi; Giovanni Tripepi; Annalisa Pitino; Roberta Ramonda; Antonio Marchesoni
Journal:  J Clin Med       Date:  2022-06-20       Impact factor: 4.964

7.  Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab.

Authors:  Frank Behrens; Michaela Koehm; Eva C Schwaneck; Marc Schmalzing; Holger Gnann; Gerd Greger; Hans-Peter Tony; Harald Burkhardt
Journal:  Rheumatology (Oxford)       Date:  2018-11-01       Impact factor: 7.580

  7 in total

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