Literature DB >> 2693198

Proteolytic enzymes from recombinant Streptomyces lividans TK24.

W Aretz1, K P Koller, G Riess.   

Abstract

Different proteases from the culture fluids of recombinant Streptomyces lividans strains were isolated. Several individual proteases were separated and characterized. A chymotrypsin-chylike activity (CLA) was identified that specifically degrades a fusion protein between the alpha-amylase inhibitor from S. tendae (Tendamistat, HOE467) and proinsulin from the monkey Macaca fascicularis. The effective chemical inhibition of the degrading enzyme is demonstrated.

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Year:  1989        PMID： 2693198     DOI： 10.1016/0378-1097(89)90361-3

Source DB:  PubMed          Journal:  FEMS Microbiol Lett        ISSN： 0378-1097            Impact factor:   2.742


  11 in total

1.  Cloning and sequencing of a gene encoding a novel extracellular neutral proteinase from Streptomyces sp. strain C5 and expression of the gene in Streptomyces lividans 1326.

Authors:  J S Lampel; J S Aphale; K A Lampel; W R Strohl
Journal:  J Bacteriol       Date:  1992-05       Impact factor: 3.490

2.  Cloning and analysis of a gene from Streptomyces lividans 66 encoding a novel secreted protease exhibiting homology to subtilisin BPN'.

Authors:  M J Butler; J S Aphale; C Binnie; M A DiZonno; P Krygsman; G Soltes; E Walczyk; L T Malek
Journal:  Appl Microbiol Biotechnol       Date:  1996-03       Impact factor: 4.813

3.  Intracellular aminopeptidases in Streptomyces lividans 66.

Authors:  M J Butler; J S Aphale; M A DiZonno; P Krygsman; E Walczyk; L T Malek
Journal:  J Ind Microbiol       Date:  1994-01

4.  High yield fermentation and purification of Tendamistat disulphide analogues secreted by Streptomyces lividans.

Authors:  S Haas-Lauterbach; M Scharf; B Sprunkel; M Neeb; K P Koller; J W Engels
Journal:  Appl Microbiol Biotechnol       Date:  1993-03       Impact factor: 4.813

5.  Molecular characterization of a gene encoding extracellular serine protease isolated from a subtilisin inhibitor-deficient mutant of Streptomyces albogriseolus S-3253.

Authors:  S Taguchi; A Odaka; Y Watanabe; H Momose
Journal:  Appl Environ Microbiol       Date:  1995-01       Impact factor: 4.792

6.  Cloning and characterization of a gene encoding a secreted tripeptidyl aminopeptidase from Streptomyces lividans 66.

Authors:  M J Butler; C Binnie; M A DiZonno; P Krygsman; G A Soltes; G Soostmeyer; E Walczyk; L T Malek
Journal:  Appl Environ Microbiol       Date:  1995-08       Impact factor: 4.792

7.  Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan.

Authors:  Marie-Pierre Dubeau; Isabelle Guay; Ryszard Brzezinski
Journal:  Microb Cell Fact       Date:  2011-02-10       Impact factor: 5.328

8.  The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks.

Authors:  Ramsés A Gamboa-Suasnavart; Norma A Valdez-Cruz; Laura E Cordova-Dávalos; José A Martínez-Sotelo; Luis Servín-González; Clara Espitia; Mauricio A Trujillo-Roldán
Journal:  Microb Cell Fact       Date:  2011-12-20       Impact factor: 5.328

9.  Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans.

Authors:  Elsa Pimienta; Julio C Ayala; Caridad Rodríguez; Astrid Ramos; Lieve Van Mellaert; Carlos Vallín; Jozef Anné
Journal:  Microb Cell Fact       Date:  2007-07-05       Impact factor: 5.328

10.  Streptomyces flavogriseus HS1: isolation and characterization of extracellular proteases and their compatibility with laundry detergents.

Authors:  Sofiane Ghorbel; Maher Kammoun; Hala Soltana; Moncef Nasri; Noomen Hmidet
Journal:  Biomed Res Int       Date:  2014-04-06       Impact factor: 3.411
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