Literature DB >> 2692956

Insulin-like growth factor (IGF) and bone.

T L McCarthy1, M Centrella, E Canalis.   

Abstract

Bone is not only a rich source of a diverse group of growth factors, but is also a very responsive tissue to such growth promoting agents. IGF-I and IGF-II are reported to be synthesized and retained in bone. While both IGF-I and IGF-II stimulate DNA, collagen, and noncollagenous protein synthesis in cultured calvariae, these explant cultures have quantitative differential sensitivities to these IGF's. In addition to the observed increase in collagen synthesis, collagen degradation decreased in calvariae treated with IGF-I or IGF-II.

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Year:  1989        PMID： 2692956     DOI： 10.3109/03008208909023897

Source DB:  PubMed          Journal:  Connect Tissue Res        ISSN： 0300-8207            Impact factor:   3.417


  25 in total

1.  Serum insulin-like growth factor-I is a marker for assessing the severity of vertebral fractures in postmenopausal women with type 2 diabetes mellitus.

Authors:  I Kanazawa; T Yamaguchi; T Sugimoto
Journal:  Osteoporos Int       Date:  2010-06-08       Impact factor: 4.507

2.  Serum levels of insulin-like growth factor (IGF); IGF-binding proteins-3, -4, and -5; and their relationships to bone mineral density and the risk of vertebral fractures in postmenopausal women.

Authors:  T Yamaguchi; M Kanatani; M Yamauchi; H Kaji; T Sugishita; D J Baylink; S Mohan; K Chihara; T Sugimoto
Journal:  Calcif Tissue Int       Date:  2006-01-06       Impact factor: 4.333

3.  Bone fragility in type 2 diabetes mellitus.

Authors:  Toru Yamaguchi
Journal:  World J Orthop       Date:  2010-11-18

4.  Stratified control of IGF-I expression by hypoxia and stress hormones in osteoblasts.

Authors:  Thomas L McCarthy; Zhong Yun; Joseph A Madri; Michael Centrella
Journal:  Gene       Date:  2014-01-15       Impact factor: 3.688

5.  Immunoexpression of IGF1, IGF2, and osteopontin in craniofacial bone repair associated with autogenous grafting in rat models treated with alendronate sodium.

Authors:  Paulo Roberto Camati; Allan Fernando Giovanini; Hugo Eduardo de Miranda Peixoto; Cassiana Majewski Schuanka; Maria Cecília Giacomel; Melissa Rodrigues de Araújo; João César Zielak; Rafaela Scariot; Tatiana Miranda Deliberador
Journal:  Clin Oral Investig       Date:  2016-10-22       Impact factor: 3.573

6.  Osteosarcopenia in Reproductive-Aged Women with Polycystic Ovary Syndrome: A Multicenter Case-Control Study.

Authors:  Maryam Kazemi; Brittany Y Jarrett; Stephen A Parry; Anna E Thalacker-Mercer; Kathleen M Hoeger; Steven D Spandorfer; Marla E Lujan
Journal:  J Clin Endocrinol Metab       Date:  2020-09-01       Impact factor: 5.958

7.  Mechanical properties, bone mineral content, and bone composition (collagen, osteocalcin, IGF-I) of the rat femur: influence of ovariectomy and nandrolone decanoate (anabolic steroid) treatment.

Authors:  J Aerssens; R Van Audekercke; P Geusens; L P Schot; A A Osman; J Dequeker
Journal:  Calcif Tissue Int       Date:  1993-10       Impact factor: 4.333

8.  Enhancement of osteoblast proliferative capacity by growth factor-like molecules in bear serum.

Authors:  Michael Overstreet; Timothy Floyd; Anna Polotsky; David S Hungerford; Carmelita G Frondoza
Journal:  In Vitro Cell Dev Biol Anim       Date:  2003 Jan-Feb       Impact factor: 2.416

9.  Serum levels of insulin-like growth factor (IGF)-I and IGF binding protein (IGFBP)-1 to -6 and their relationship to bone metabolism in osteoporosis patients.

Authors:  Peter M. Jehle; Klaus Schulten; Walter Schulz; Daniela R. Jehle; Sylvia Stracke; Burkhard Manfras; Bernhard O. Boehm; David J. Baylink; Subburaman Mohan
Journal:  Eur J Intern Med       Date:  2003-02       Impact factor: 4.487

10.  Determination of the histological distribution of insulin like growth factor 1 receptors in the rat gut.

Authors:  J Ryan; D C Costigan
Journal:  Gut       Date:  1993-12       Impact factor: 23.059
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