OBJECTIVE/ BACKGROUND: Tuberculosis (TB) is a major cause of morbidity and mortality in developing countries. Passive case detection in national TB programmes is associated with low case notification, especially in children. This study was undertaken to improve detection of childhood TB in resource-poor settings through intensified case-finding strategies. METHODS: A community-based intervention was carried out in six states in Nigeria. The creation of TB awareness was undertaken, and work aids, guidelines, and diagnostic charts were produced, distributed, and used. Various cadres of health workers and ad hoc project staff were trained. Child contacts with TB patients were screened in their homes, and children presenting at various hospital units were screened for TB. Baseline and intervention data were collected for evaluation populations and control populations. RESULTS: Detection of childhood TB increased in the evaluation population during the intervention, with a mean quarterly increase of 4.0% [new smear positive (NSP), although the increasing trend was not statistically significant (χ(2)=1.8; p<.179)]. Additionally, there was a mean quarterly increase of 3% for all forms of TB, although the trend was not statistically significant (χ(2)=1.48; p<.224). Conversely, there was a decrease in case notification in the control population, with a mean decline of 3% (all forms). Compared to the baseline, there was an increase of 31% (all forms) and 22% (NSP) in the evaluation population. CONCLUSION: Intensified case finding combined with capacity building, provision of work aids/guidelines, and TB health education can improve childhood-TB notification.
OBJECTIVE/ BACKGROUND:Tuberculosis (TB) is a major cause of morbidity and mortality in developing countries. Passive case detection in national TB programmes is associated with low case notification, especially in children. This study was undertaken to improve detection of childhood TB in resource-poor settings through intensified case-finding strategies. METHODS: A community-based intervention was carried out in six states in Nigeria. The creation of TB awareness was undertaken, and work aids, guidelines, and diagnostic charts were produced, distributed, and used. Various cadres of health workers and ad hoc project staff were trained. Child contacts with TB patients were screened in their homes, and children presenting at various hospital units were screened for TB. Baseline and intervention data were collected for evaluation populations and control populations. RESULTS: Detection of childhood TB increased in the evaluation population during the intervention, with a mean quarterly increase of 4.0% [new smear positive (NSP), although the increasing trend was not statistically significant (χ(2)=1.8; p<.179)]. Additionally, there was a mean quarterly increase of 3% for all forms of TB, although the trend was not statistically significant (χ(2)=1.48; p<.224). Conversely, there was a decrease in case notification in the control population, with a mean decline of 3% (all forms). Compared to the baseline, there was an increase of 31% (all forms) and 22% (NSP) in the evaluation population. CONCLUSION: Intensified case finding combined with capacity building, provision of work aids/guidelines, and TB health education can improve childhood-TB notification.
Authors: Melanie M Dubois; Meredith B Brooks; Amyn A Malik; Sara Siddiqui; Junaid F Ahmed; Maria Jaswal; Farhana Amanullah; Mercedes C Becerra; Hamidah Hussain Journal: Pediatr Infect Dis J Date: 2022-07-13 Impact factor: 3.806
Authors: L Bosa; L Da Silva; D V Mendes; A Sifna; M Sargento Mendes; F Riccardi; R Colombatti Journal: Mediterr J Hematol Infect Dis Date: 2017-10-15 Impact factor: 2.576
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Authors: Amyn A Malik; Hamidah Hussain; Jacob Creswell; Sara Siddiqui; Junaid F Ahmed; Falak Madhani; Ali Habib; Aamir J Khan; Farhana Amanullah Journal: Trop Med Infect Dis Date: 2019-12-15
Authors: O O Chijioke-Akaniro; E Ubochioma; A Omoniyi; O Fashade; O Olarewaju; S Asuke; E C Aniwada; A N Uwaezuoke; J Sseskitooleko; N Workneh; E Masini; B Morris; A Lawanson; C Anyaike Journal: Public Health Action Date: 2022-09-21
Authors: Emmanuel Pembi; Stephen John; Shyam Prakash Dumre; Baba Usman Ahmadu; Nguyen Lam Vuong; Amr Ebied; Shusaku Mizukami; Nguyen Tien Huy; Luis E Cuevas; Kenji Hirayama Journal: BMJ Open Date: 2020-09-16 Impact factor: 2.692