| Literature DB >> 26926585 |
Leonardo Pasalic1, Samuel S Y Wang2, Vivien M Y Chen1.
Abstract
Primary and secondary prevention of cardiovascular disease remain a public health priority. Effective risk stratification of patients is a central requisite for effective preventative care and several scoring systems incorporating biomarkers have been used for prognostication in patients to guide intervention decisions. Thrombosis of atherosclerotic coronary arteries is the main mechanism behind the acute coronary syndromes and since platelets play a pivotal role in the pathogenesis of thrombosis, atherogenesis, and angiogenesis, platelet-derived biomarkers are an attractive concept. This review assesses the potential and the limitations of a range of platelet-based assays as biomarkers for coronary artery disease. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Entities:
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Year: 2016 PMID: 26926585 DOI: 10.1055/s-0036-1572328
Source DB: PubMed Journal: Semin Thromb Hemost ISSN: 0094-6176 Impact factor: 4.180