Literature DB >> 26926577

Distinguishing N-acetylneuraminic acid linkage isomers on glycopeptides by ion mobility-mass spectrometry.

H Hinneburg1, J Hofmann2, W B Struwe3, A Thader4, F Altmann4, D Varón Silva5, P H Seeberger1, K Pagel2, D Kolarich5.   

Abstract

Differentiating the structure of isobaric glycopeptides represents a major challenge for mass spectrometry-based characterisation techniques. Here we show that the regiochemistry of the most common N-acetylneuraminic acid linkages of N-glycans can be identified in a site-specific manner from individual glycopeptides using ion mobility-mass spectrometry analysis of diagnostic fragment ions.

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Year:  2016        PMID： 26926577     DOI： 10.1039/c6cc01114d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  28 in total

Review 1.  Recent advances in ion mobility-mass spectrometry for improved structural characterization of glycans and glycoconjugates.

Authors:  Zhengwei Chen; Matthew S Glover; Lingjun Li
Journal:  Curr Opin Chem Biol       Date:  2017-11-05       Impact factor: 8.822

2.  Structural Studies of Fucosylated N-Glycans by Ion Mobility Mass Spectrometry and Collision-Induced Fragmentation of Negative Ions.

Authors:  David J Harvey; Weston B Struwe
Journal:  J Am Soc Mass Spectrom       Date:  2018-05-22       Impact factor: 3.109

Review 3.  Recent Advances in the Analysis of Complex Glycoproteins.

Authors:  Stefan Gaunitz; Gabe Nagy; Nicola L B Pohl; Milos V Novotny
Journal:  Anal Chem       Date:  2016-11-23       Impact factor: 6.986

4.  Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations.

Authors:  Gabe Nagy; Isaac K Attah; Sandilya V B Garimella; Keqi Tang; Yehia M Ibrahim; Erin S Baker; Richard D Smith
Journal:  Chem Commun (Camb)       Date:  2018-09-28       Impact factor: 6.222

5.  Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.

Authors:  David J Harvey; Charlotte A Scarff; Matthew Edgeworth; Kevin Pagel; Konstantinos Thalassinos; Weston B Struwe; Max Crispin; James H Scrivens
Journal:  J Mass Spectrom       Date:  2016-11       Impact factor: 1.982

6.  Identifying Sialylation Linkages at the Glycopeptide Level by Glycosyltransferase Labeling Assisted Mass Spectrometry (GLAMS).

Authors:  He Zhu; Shuaishuai Wang; Ding Liu; Lang Ding; Congcong Chen; Yunpeng Liu; Zhigang Wu; Roni Bollag; Kebin Liu; William Max Alexander; Jun Yin; Cheng Ma; Lei Li; Peng George Wang
Journal:  Anal Chem       Date:  2020-04-15       Impact factor: 6.986

7.  Isolation and characterization of glycosylated neuropeptides.

Authors:  Yang Liu; Qinjingwen Cao; Lingjun Li
Journal:  Methods Enzymol       Date:  2019-08-12       Impact factor: 1.600

8.  Site-Specific Mapping of Sialic Acid Linkage Isomers by Ion Mobility Spectrometry.

Authors:  Miklos Guttman; Kelly K Lee
Journal:  Anal Chem       Date:  2016-05-02       Impact factor: 6.986

Review 9.  Mass Spectrometry Approaches to Glycomic and Glycoproteomic Analyses.

Authors:  L Renee Ruhaak; Gege Xu; Qiongyu Li; Elisha Goonatilleke; Carlito B Lebrilla
Journal:  Chem Rev       Date:  2018-03-19       Impact factor: 60.622

Review 10.  Recent advances in mass spectrometric analysis of glycoproteins.

Authors:  Alireza Banazadeh; Lucas Veillon; Kerry M Wooding; Masoud Zabet-Moghaddam; Yehia Mechref
Journal:  Electrophoresis       Date:  2016-12-15       Impact factor: 3.535
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