| Literature DB >> 2692562 |
S Maeda1.
Abstract
Genetically engineered insect viruses may be potential alternatives to conventional chemical insecticides. A recombinant gene for the diuretic hormone of the tobacco hornworm, Manduca sexta, has been introduced into a baculovirus, Bombyx mori nuclear polyhedrosis virus (BmNPV). When silkworm larvae were injected with the resulting recombinant BmNPV, the diuretic hormone was expressed, causing a strong alteration in larval fluid metabolism. The recombinant virus killed infected larvae about 20% faster than the original virus.Entities:
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Year: 1989 PMID: 2692562 DOI: 10.1016/0006-291x(89)92726-5
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN: 0006-291X Impact factor: 3.575