Literature DB >> 2692560

Free calcium rise and mitogenesis in glial cells caused by endothelin.

S Supattapone1, A W Simpson, C C Ashley.   

Abstract

The peptide endothelin causes a biphasic rise in intracellular free calcium levels in cultured Type-1 astrocytes and C6 glioma cells, suggesting that glial cells may be the physiological target of endothelin in the brain. Endothelin also causes a calcium-dependent increase [3H]thymidine incorporation in primary cultures of rat cerebellum, indicating that, among other possible roles, this peptide may mediate mitogenesis in brain.

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Year:  1989        PMID： 2692560     DOI： 10.1016/0006-291x(89)92718-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  14 in total

1.  Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells.

Authors:  M W MacCumber; C A Ross; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

2.  Combinatorial targeting of early pathways profoundly inhibits neurodegeneration in a mouse model of glaucoma.

Authors:  Gareth R Howell; Katharine H MacNicoll; Catherine E Braine; Ileana Soto; Danilo G Macalinao; Gregory L Sousa; Simon W M John
Journal:  Neurobiol Dis       Date:  2014-08-15       Impact factor: 5.996

3.  Characterization of [125I]-endothelin-1 and [125I]-BQ3020 binding to rat cerebellar endothelin receptors.

Authors:  P S Widdowson; C N Kirk
Journal:  Br J Pharmacol       Date:  1996-08       Impact factor: 8.739

4.  Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis.

Authors:  C Serradeil-Le Gal; C Jouneaux; A Sanchez-Bueno; D Raufaste; B Roche; A M Préaux; J P Maffrand; P H Cobbold; J Hanoune; S Lotersztajn
Journal:  J Clin Invest       Date:  1991-01       Impact factor: 14.808

5.  Localisation of endothelin like immunoreactivity in adult and developing human gut.

Authors:  C Escrig; A E Bishop; H Inagaki; G Moscoso; K Takahashi; I M Varndell; M A Ghatei; S R Bloom; J M Polak
Journal:  Gut       Date:  1992-02       Impact factor: 23.059

6.  Involvement of local ischemia in endothelin-1 induced lesions of the neostriatum of the anaesthetized rat.

Authors:  K Fuxe; N Kurosawa; A Cintra; A Hallström; M Goiny; L Rosén; L F Agnati; U Ungerstedt
Journal:  Exp Brain Res       Date:  1992       Impact factor: 1.972

7.  Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factor.

Authors:  R M Hu; E R Levin
Journal:  J Clin Invest       Date:  1994-04       Impact factor: 14.808

8.  Endothelin-3 stimulates inositol 1,4,5-trisphosphate production and Ca2+ influx to produce biphasic dopamine release from rat striatal slices.

Authors:  Y Kataoka; S Koizumi; M Niwa; H Shibaguchi; K Shigematsu; Y Kudo; K Taniyama
Journal:  Cell Mol Neurobiol       Date:  1994-06       Impact factor: 5.046

9.  Calcium mobilization induced by endothelins and sarafotoxin in cultured canine tracheal smooth muscle cells.

Authors:  C M Yang; Y L Yo; R Ong; J T Hsieh; H L Tsao
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1994-07       Impact factor: 3.000

10.  Endothelin-1 regulates oligodendrocyte development.

Authors:  Ana Gadea; Adan Aguirre; Tarik F Haydar; Vittorio Gallo
Journal:  J Neurosci       Date:  2009-08-12       Impact factor: 6.167
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