Literature DB >> 26924628

Cell-based Assays for Assessing Toxicity: A Basic Guide.

Raveen Parboosing1, Gugulethu Mzobe, Louis Chonco, Indres Moodley.   

Abstract

Assessment of toxicity is an important component of the drug discovery process. Cellbased assays are a popular choice for assessing cytotoxicity. However, these assays are complex because of the wide variety of formats and methods that are available, lack of standardization, confusing terminology and the inherent variability of biological systems and measurement. This review is intended as a guide on how to take these factors into account when planning, conducting and/or interpreting cell based toxicity assays. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Cytotoxicity; apoptosis; cell-based assays; cytotoxicity screening; toxicity.; viability assays

Mesh:

Year:  2016        PMID: 26924628     DOI: 10.2174/1573406412666160229150803

Source DB:  PubMed          Journal:  Med Chem        ISSN: 1573-4064            Impact factor:   2.745


  3 in total

1.  Preparation of a novel injectable in situ-gelling nanoparticle with applications in controlled protein release and cancer cell entrapment.

Authors:  Min Kyung Khang; Jun Zhou; Yihui Huang; Amirhossein Hakamivala; Liping Tang
Journal:  RSC Adv       Date:  2018-10-09       Impact factor: 4.036

2.  Phenotype-Based Threat Assessment.

Authors:  Jing Yang; Mohammed Eslami; Yi-Pei Chen; Mayukh Das; Dongmei Zhang; Shaorong Chen; Alexandria-Jade Roberts; Mark Weston; Angelina Volkova; Kasra Faghihi; Robbie K Moore; Robert C Alaniz; Alice R Wattam; Allan Dickerman; Clark Cucinell; Jarred Kendziorski; Sean Coburn; Holly Paterson; Osahon Obanor; Jason Maples; Stephanie Servetas; Jennifer Dootz; Qing-Ming Qin; James E Samuel; Arum Han; Erin J van Schaik; Paul de Figueiredo
Journal:  Proc Natl Acad Sci U S A       Date:  2022-04-01       Impact factor: 12.779

3.  In-Depth Characterization of Zika Virus Inhibitors Using Cell-Based Electrical Impedance.

Authors:  Merel Oeyen; Eef Meyen; Jordi Doijen; Dominique Schols
Journal:  Microbiol Spectr       Date:  2022-07-11
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.