| Literature DB >> 26924628 |
Raveen Parboosing1, Gugulethu Mzobe, Louis Chonco, Indres Moodley.
Abstract
Assessment of toxicity is an important component of the drug discovery process. Cellbased assays are a popular choice for assessing cytotoxicity. However, these assays are complex because of the wide variety of formats and methods that are available, lack of standardization, confusing terminology and the inherent variability of biological systems and measurement. This review is intended as a guide on how to take these factors into account when planning, conducting and/or interpreting cell based toxicity assays. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.Entities:
Keywords: Cytotoxicity; apoptosis; cell-based assays; cytotoxicity screening; toxicity.; viability assays
Mesh:
Year: 2016 PMID: 26924628 DOI: 10.2174/1573406412666160229150803
Source DB: PubMed Journal: Med Chem ISSN: 1573-4064 Impact factor: 2.745