Literature DB >> 26924198

[Treatment of cardiovascular risk factors].

K Krüger1.   

Abstract

Cardiovascular (CV) events are among the most important comorbidities and are the major cause of death in inflammatory rheumatic diseases, such as rheumatoid arthritis (RA). Disease activity and traditional CV risk factors contribute to the total CV risk. Among the antirheumatic drugs used for long-term treatment of RA, non-steroidal anti-inflammatory drugs (NSAID) and glucocorticoids lead to an increased risk but disease-modifying antirheumatic drugs (DMARD), such as hydroxychloroquine, methotrexate and especially biologics significantly reduce the risk. Besides achieving the best possible disease control, rheumatologists should identify additional CV risk factors and also initiate adequate treatment in order to reduce or even eliminate the CV risk. When treating rheumatic diseases possible drug-induced elevation of CV risk must be considered. Finally, the CV risk should be regularly monitored.

Entities:  

Keywords:  Antirheumatic drugs; Biologics; Glucocorticoids; Myocardial infarction; Rheumatoid arthritis

Mesh:

Substances:

Year:  2016        PMID: 26924198     DOI: 10.1007/s00393-016-0064-8

Source DB:  PubMed          Journal:  Z Rheumatol        ISSN: 0340-1855            Impact factor:   1.372


  31 in total

1.  EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis.

Authors:  M J L Peters; D P M Symmons; D McCarey; B A C Dijkmans; P Nicola; T K Kvien; I B McInnes; H Haentzschel; M A Gonzalez-Gay; S Provan; A Semb; P Sidiropoulos; G Kitas; Y M Smulders; M Soubrier; Z Szekanecz; N Sattar; M T Nurmohamed
Journal:  Ann Rheum Dis       Date:  2009-09-22       Impact factor: 19.103

Review 2.  [Cardiovascular comorbidity and its risk factors in rheumatoid arthritis].

Authors:  S Kleinert; K Krueger
Journal:  Z Rheumatol       Date:  2011-08       Impact factor: 1.372

3.  Risk factors for the rapid increase in risk of acute coronary events in patients with new-onset rheumatoid arthritis: a nested case-control study.

Authors:  Ängla Mantel; Marie Holmqvist; Fredrik Nyberg; Göran Tornling; Thomas Frisell; Lars Alfredsson; Johan Askling
Journal:  Arthritis Rheumatol       Date:  2015-11       Impact factor: 10.995

4.  Results from systematic screening for cardiovascular risk in outpatients with rheumatoid arthritis in accordance with the EULAR recommendations.

Authors:  Jette Primdahl; Joan Clausen; Kim Hørslev-Petersen
Journal:  Ann Rheum Dis       Date:  2013-07-12       Impact factor: 19.103

5.  Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register.

Authors:  K L Hyrich; K D Watson; A J Silman; D P M Symmons
Journal:  Rheumatology (Oxford)       Date:  2006-05-16       Impact factor: 7.580

Review 6.  Cardiovascular comorbidity in rheumatic diseases.

Authors:  Michael T Nurmohamed; Maaike Heslinga; George D Kitas
Journal:  Nat Rev Rheumatol       Date:  2015-08-18       Impact factor: 20.543

7.  Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial.

Authors:  David W McCarey; Iain B McInnes; Rajan Madhok; Rosie Hampson; Olga Scherbakov; Ian Ford; Hilary A Capell; Naveed Sattar
Journal:  Lancet       Date:  2004-06-19       Impact factor: 79.321

8.  Associations of hydroxychloroquine use with lipid profiles in rheumatoid arthritis: pharmacologic implications.

Authors:  Gail Kerr; Mireille Aujero; John Richards; Harlan Sayles; Lisa Davis; Grant Cannon; Liron Caplan; Kaleb Michaud; Ted Mikuls
Journal:  Arthritis Care Res (Hoboken)       Date:  2014-11       Impact factor: 4.794

Review 9.  The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis.

Authors:  Leena R Baghdadi; Richard J Woodman; E Michael Shanahan; Arduino A Mangoni
Journal:  PLoS One       Date:  2015-02-17       Impact factor: 3.240

10.  Longer durations of antitumour necrosis factor treatment are associated with reduced risk of cardiovascular events in patients with rheumatoid arthritis.

Authors:  Michael Nurmohamed; Yanjun Bao; James Signorovitch; Alex Trahey; Parvez Mulani; Daniel E Furst
Journal:  RMD Open       Date:  2015-05-21
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  3 in total

Review 1.  Cardiovascular Comorbidity in Inflammatory Rheumatological Conditions.

Authors:  Jürgen Braun; Klaus Krüger; Bernhard Manger; Matthias Schneider; Christof Specker; Hans Joachim Trappe
Journal:  Dtsch Arztebl Int       Date:  2017-03-24       Impact factor: 5.594

Review 2.  [Pharmacological treatment of rheumatoid arthritis and its comorbidities].

Authors:  K Krüger
Journal:  Internist (Berl)       Date:  2018-04       Impact factor: 0.743

Review 3.  [Biologics and further new drugs for rheumatic diseases since 2000].

Authors:  K Krüger
Journal:  Orthopade       Date:  2018-11       Impact factor: 1.087

  3 in total

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