| Literature DB >> 26923771 |
Xin Li1, Hao Jiang2, Zhaofeng Luo2, Young-Tae Chang3, Liyun Zhang1.
Abstract
A fluorescent sensor - InR - with disaggregation-induced emission (DIE) characteristics has been developed for the label free detection of RecA inteins from Mycobacterium tuberculosis. Mechanistic studies demonstrate that InR binds at a hydrophobic pocket of RecA inteins, which is constituted by Gly435, Glu434, Arg405 and Arg 7, resulting in the disaggregation and recovery of its fluorescence.Entities:
Mesh：
Substances：
Year: 2016 PMID： 26923771 DOI： 10.1039/c6cc00439c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222