Literature DB >> 26923631

Liver resection in the elderly: A retrospective cohort study of 460 patients - Feasible and safe.

Anne Andert1, Toine Lodewick2, Tom Florian Ulmer3, Max Schmeding3, Wenzel Schöning3, Ulf Neumann3, Kees Dejong2, Christoph Heidenhain3.   

Abstract

INTRODUCTION: The aim of this study was to determine the influence of age on the early postoperative outcome after liver surgery.
MATERIAL AND METHODS: Between January 2005 and July 2012 460 hepatic resections were performed in patients aged 60 years or younger and 70 years or older at the University Hospital Aachen and University Hospital Maastricht. The postoperative outcome of hepatic resection was evaluated by the time of intensive care unit (ICU) stay, length of hospital stay, appearance of postoperative complications and in-hospital mortality.
RESULTS: The median postoperative hospital stay was 7 days in group ≤60 and 8 days in group ≥70 (p = 0.007). The median time of ICU stay was 1 day in both groups. There were no statistically significant differences according to liver related complications. In group ≥70, significantly more patients suffered from pneumonia (8% vs. 2% in group ≤60, p = 0.015). The overall mortality rate was 3.5%.
CONCLUSION: Age alone should not be a contraindication for liver resection. However, elderly patients who develop pneumonia are at high risk for postoperative mortality. Therefore, factors such as short time of invasive ventilation, direct and intensive respiratory therapy and mobilization are of particular importance and should be focused on even more.
Copyright © 2016. Published by Elsevier Ltd.

Entities:  

Keywords:  Elderly patients; Liver resection

Mesh:

Year:  2016        PMID: 26923631     DOI: 10.1016/j.ijsu.2016.02.060

Source DB:  PubMed          Journal:  Int J Surg        ISSN: 1743-9159            Impact factor:   6.071


  4 in total

1.  Effect of Age (over 75 Years) on Postoperative Complications and Survival in Patients Undergoing Hepatic Resection for Hepatocellular Carcinoma.

Authors:  Roberto Santambrogio; Matteo Barabino; Giovanna Scifo; Mara Costa; Marco Giovenzana; Enrico Opocher
Journal:  J Gastrointest Surg       Date:  2017-01-12       Impact factor: 3.452

2.  Liver Transplantation and Liver Resection for Cirrhotic Patients with Hepatocellular Carcinoma: Comparison of Long-Term Survivals.

Authors:  Felix Krenzien; Moritz Schmelzle; Benjamin Struecker; Nathanael Raschzok; Christian Benzing; Maximilian Jara; Marcus Bahra; Robert Öllinger; Igor M Sauer; Andreas Pascher; Johann Pratschke; Andreas Andreou
Journal:  J Gastrointest Surg       Date:  2018-01-23       Impact factor: 3.452

3.  Short- and Long-Term Outcomes After Hepatectomy in Elderly Patients with Hepatocellular Carcinoma: An Analysis of 229 Cases from a Developing Country.

Authors:  Danijel Galun; Aleksandar Bogdanovic; Marko Zivanovic; Marinko Zuvela
Journal:  J Hepatocell Carcinoma       Date:  2021-03-23

4.  Resection of intrahepatic cholangiocarcinoma in elderly patients - is it reasonable?

Authors:  Fabian Bartsch; Janine Baumgart; Verena Tripke; Maria Hoppe-Lotichius; Stefan Heinrich; Hauke Lang
Journal:  BMC Surg       Date:  2019-10-29       Impact factor: 2.102

  4 in total

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