Literature DB >> 26923175

Direct visualization of replication dynamics in early zebrafish embryos.

Kenji Kuriya1, Eriko Higashiyama1, Eriko Avşar-Ban2, Nanami Okochi1, Kaede Hattori1, Shin Ogata1, Shin-Ichiro Takebayashi3, Masato Ogata3, Yutaka Tamaru2, Katsuzumi Okumura1.   

Abstract

We analyzed DNA replication in early zebrafish embryos. The replicating DNA of whole embryos was labeled with the thymidine analog 5-ethynyl-2'-deoxyuridine (EdU), and spatial regulation of replication sites was visualized in single embryo-derived cells. The results unveiled uncharacterized replication dynamics during zebrafish early embryogenesis.

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Keywords:  DNA replication; replication foci; zebrafish embryo

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Year:  2016        PMID： 26923175     DOI： 10.1080/09168451.2016.1141039

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  2 in total

1.  Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2'-Deoxyuridine and 5-Bromo-2'-Deoxyurdine to Mammalian Cells.

Authors:  Jeremy S Haskins; Cathy Su; Junko Maeda; Kade D Walsh; Alexis H Haskins; Allison J Allum; Coral E Froning; Takamitsu A Kato
Journal:  Int J Mol Sci       Date:  2020-09-10       Impact factor: 5.923

2.  Combined Developmental Toxicity of the Pesticides Difenoconazole and Dimethomorph on Embryonic Zebrafish.

Authors:  Ruiqi Fan; Wanjun Zhang; Li Jia; Lizhong Li; Jun Zhao; Zengming Zhao; Shuangqing Peng; Yiqiang Chen; Xiaoyan Yuan
Journal:  Toxins (Basel)       Date:  2021-12-01       Impact factor: 4.546
  2 in total

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