Laia Rodríguez-Cintas1, Constanza Daigre2, Lara Grau-López3, Carmen Barral3, Jesús Pérez-Pazos4, Núria Voltes5, María Dolores Braquehais6, Miquel Casas6, Carlos Roncero3. 1. Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address: lairodri@vhebron.net. 2. Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. 3. Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry, Vall d'Hebron University Hospital, CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. 4. Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain; Department of Psychiatry, Vall d'Hebron University Hospital, CIBERSAM, Barcelona, Spain. 5. Addiction and Dual Diagnosis Unit, Department of Psychiatry, Vall d'Hebron University Hospital - Public Health Agency, Barcelona (ASPB), CIBERSAM, Barcelona, Spain. 6. Department of Psychiatry, Vall d'Hebron University Hospital, CIBERSAM, Barcelona, Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.
Abstract
BACKGROUND: Impulsivity as a personality trait is a risk factor for the development and maintenance of cocaine and opioid dependence. The objective of this study is to analyze the relationship between impulsivity and addiction severity in cocaine and opioid dependent patients. METHODS: A cross-sectional, observational study of 526 patients with lifetime cocaine dependence (CD, n=351), opiate dependence (OD, n=51) and comorbid cocaine and opiate dependence (COD, n=124) to throughout life, according to DSM-IV-TR, was conducted. The sample was recruited at the Addiction and Dual Diagnosis Unit of Vall d'Hebron University Hospital from January 2006 to April 2013. Patients were evaluated with the EuropASI, the SCID I and II interviews, and the Barratt Impulsivity Scale (BIS-11). Descriptive statistics of the main variables (including mean, standard deviation) was performed. Chi square test was used to compare categorical variables and Kruskal-Wallis test to compare continuous variables. Spearman correlation was used to analyze the relationship between EuropASI scores and BIS-11 scores. RESULTS: The mean age of the patients was 36.37years±8.08 (19-66). CD and COD were more impulsive and had higher addiction severity than OD. OD patients had worse medical status than CD and COD patients while COD patients had more severe drug use and legal problems than the other groups. However, impulsivity and addiction severity were only positively correlated in CD patients. CONCLUSIONS: Impulsivity should be appropriately screened and addressed in cocaine dependents as it may be related to addiction severity.
BACKGROUND:Impulsivity as a personality trait is a risk factor for the development and maintenance of cocaine and opioid dependence. The objective of this study is to analyze the relationship between impulsivity and addiction severity in cocaine and opioid dependent patients. METHODS: A cross-sectional, observational study of 526 patients with lifetime cocaine dependence (CD, n=351), opiate dependence (OD, n=51) and comorbid cocaine and opiate dependence (COD, n=124) to throughout life, according to DSM-IV-TR, was conducted. The sample was recruited at the Addiction and Dual Diagnosis Unit of Vall d'Hebron University Hospital from January 2006 to April 2013. Patients were evaluated with the EuropASI, the SCID I and II interviews, and the Barratt Impulsivity Scale (BIS-11). Descriptive statistics of the main variables (including mean, standard deviation) was performed. Chi square test was used to compare categorical variables and Kruskal-Wallis test to compare continuous variables. Spearman correlation was used to analyze the relationship between EuropASI scores and BIS-11 scores. RESULTS: The mean age of the patients was 36.37years±8.08 (19-66). CD and COD were more impulsive and had higher addiction severity than OD. OD patients had worse medical status than CD and CODpatients while CODpatients had more severe drug use and legal problems than the other groups. However, impulsivity and addiction severity were only positively correlated in CDpatients. CONCLUSIONS:Impulsivity should be appropriately screened and addressed in cocaine dependents as it may be related to addiction severity.
Authors: Sandra Sanchez-Roige; Pierre Fontanillas; Sarah L Elson; Joshua C Gray; Harriet de Wit; James MacKillop; Abraham A Palmer Journal: J Neurosci Date: 2019-02-04 Impact factor: 6.167
Authors: Eduardo R Butelman; Carina Y Chen; Kimberly J Lake; Kate G Brown; Mary Jeanne Kreek Journal: Exp Clin Psychopharmacol Date: 2020-10-29 Impact factor: 3.157
Authors: Marianne L Seney; Sam-Moon Kim; Jill R Glausier; Mariah A Hildebrand; Xiangning Xue; Wei Zong; Jiebiao Wang; Micah A Shelton; BaDoi N Phan; Chaitanya Srinivasan; Andreas R Pfenning; George C Tseng; David A Lewis; Zachary Freyberg; Ryan W Logan Journal: Biol Psychiatry Date: 2021-06-12 Impact factor: 12.810
Authors: William S Hyatt; Michael D Berquist; Neha M Chitre; Lauren N Russell; Kenner C Rice; Kevin S Murnane; William E Fantegrossi Journal: Behav Pharmacol Date: 2019-10 Impact factor: 2.277
Authors: William S Hyatt; Caitlin E Hirsh; Lauren N Russell; Neha M Chitre; Kevin S Murnane; Kenner C Rice; William E Fantegrossi Journal: Behav Pharmacol Date: 2020-06 Impact factor: 2.277