Literature DB >> 26921290

Media Reporting of Practice-Changing Clinical Trials in Oncology: A North American Perspective.

Peter Andrew1, Michael M Vickers2, Stephen O'Connor3, Mario Valdes4, Patricia A Tang5.   

Abstract

INTRODUCTION: Media reporting of clinical trials impacts patient-oncologist interactions. We sought to characterize the accuracy of media and Internet reporting of practice-changing clinical trials in oncology.
MATERIALS AND METHODS: The first media articles referencing 17 practice-changing clinical trials were collected from 4 media outlets: newspapers, cable news, cancer websites, and industry websites. Measured outcomes were media reporting score, social media score, and academic citation score. The media reporting score was a measure of completeness of information detailed in media articles as scored by a 15-point scoring instrument. The social media score represented the ubiquity of social media presence referencing 17 practice-changing clinical trials in cancer as determined by the American Society of Clinical Oncology in its annual report, entitled Clinical Cancer Advances 2012; social media score was calculated from Twitter, Facebook, and Google searches. The academic citation score comprised total citations from Google Scholar plus the Scopus database, which represented the academic impact per clinical cancer advance.
RESULTS: From 170 media articles, 107 (63%) had sufficient data for analysis. Cohen's κ coefficient demonstrated reliability of the media reporting score instrument with a coefficient of determination of 94%. Per the media reporting score, information was most complete from industry, followed by cancer websites, newspapers, and cable news. The most commonly omitted items, in descending order, were study limitations, exclusion criteria, conflict of interest, and other. The social media score was weakly correlated with academic citation score.
CONCLUSION: Media outlets appear to have set a low bar for coverage of many practice-changing advances in oncology, with reports of scientific breakthroughs often omitting basic study facts and cautions, which may mislead the public. The media should be encouraged to use a standardized reporting template and provide accessible references to original source information whenever feasible. ©AlphaMed Press.

Entities:  

Keywords:  Clinical trials; Journalism; Neoplasms; Social media

Mesh:

Year:  2016        PMID: 26921290      PMCID: PMC4786362          DOI: 10.1634/theoncologist.2015-0056

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  53 in total

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2.  Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial.

Authors:  Winette T A van der Graaf; Jean-Yves Blay; Sant P Chawla; Dong-Wan Kim; Binh Bui-Nguyen; Paolo G Casali; Patrick Schöffski; Massimo Aglietta; Arthur P Staddon; Yasuo Beppu; Axel Le Cesne; Hans Gelderblom; Ian R Judson; Nobuhito Araki; Monia Ouali; Sandrine Marreaud; Rachel Hodge; Mohammed R Dewji; Corneel Coens; George D Demetri; Christopher D Fletcher; Angelo Paolo Dei Tos; Peter Hohenberger
Journal:  Lancet       Date:  2012-05-16       Impact factor: 79.321

3.  Practicing in partnership with Dr. Google: the growing effect of social media in oncology practice and research.

Authors:  Howard Jack West
Journal:  Oncologist       Date:  2013-06-28

4.  Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study.

Authors:  Arti Hurria; Kayo Togawa; Supriya G Mohile; Cynthia Owusu; Heidi D Klepin; Cary P Gross; Stuart M Lichtman; Ajeet Gajra; Smita Bhatia; Vani Katheria; Shira Klapper; Kurt Hansen; Rupal Ramani; Mark Lachs; F Lennie Wong; William P Tew
Journal:  J Clin Oncol       Date:  2011-08-01       Impact factor: 44.544

5.  Trust and sources of health information: the impact of the Internet and its implications for health care providers: findings from the first Health Information National Trends Survey.

Authors:  Bradford W Hesse; David E Nelson; Gary L Kreps; Robert T Croyle; Neeraj K Arora; Barbara K Rimer; Kasisomayajula Viswanath
Journal:  Arch Intern Med       Date:  2005 Dec 12-26

6.  Trastuzumab emtansine for HER2-positive advanced breast cancer.

Authors:  Sunil Verma; David Miles; Luca Gianni; Ian E Krop; Manfred Welslau; José Baselga; Mark Pegram; Do-Youn Oh; Véronique Diéras; Ellie Guardino; Liang Fang; Michael W Lu; Steven Olsen; Kim Blackwell
Journal:  N Engl J Med       Date:  2012-10-01       Impact factor: 91.245

7.  The use of olanzapine versus metoclopramide for the treatment of breakthrough chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy.

Authors:  Rudolph M Navari; Cindy K Nagy; Sarah E Gray
Journal:  Support Care Cancer       Date:  2013-01-12       Impact factor: 3.603

8.  Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial.

Authors:  Axel Grothey; Eric Van Cutsem; Alberto Sobrero; Salvatore Siena; Alfredo Falcone; Marc Ychou; Yves Humblet; Olivier Bouché; Laurent Mineur; Carlo Barone; Antoine Adenis; Josep Tabernero; Takayuki Yoshino; Heinz-Josef Lenz; Richard M Goldberg; Daniel J Sargent; Frank Cihon; Lisa Cupit; Andrea Wagner; Dirk Laurent
Journal:  Lancet       Date:  2012-11-22       Impact factor: 79.321

9.  Cancer patients on Twitter: a novel patient community on social media.

Authors:  Yuya Sugawara; Hiroto Narimatsu; Atsushi Hozawa; Li Shao; Katsumi Otani; Akira Fukao
Journal:  BMC Res Notes       Date:  2012-12-27

10.  Assessing citations with Google Scholar: A new feature.

Authors:  K K Mueen Ahmed
Journal:  J Pharmacol Pharmacother       Date:  2012-01
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  2 in total

Review 1.  Social Media and Internet Resources for Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN).

Authors:  Naveen Pemmaraju; Vikas Gupta; Michael A Thompson; Andrew A Lane
Journal:  Curr Hematol Malig Rep       Date:  2016-12       Impact factor: 3.952

2.  Quality of information in news media reports about the effects of health interventions: Systematic review and meta-analyses.

Authors:  Matt Oxman; Lillebeth Larun; Giordano Pérez Gaxiola; Dima Alsaid; Anila Qasim; Christopher James Rose; Karin Bischoff; Andrew David Oxman
Journal:  F1000Res       Date:  2021-06-01
  2 in total

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