Literature DB >> 26920158

Lipid Control and Beyond: Current and Future Indications for Statin Therapy in Stroke.

Shadi Yaghi1, Mitchell S V Elkind2,3.   

Abstract

OPINION STATEMENT: Statins are a group of lipid-lowering agents that are competitive inhibitors of the enzyme 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase that have been used to reduce cholesterol levels and prevent cardiovascular events. Statins have been also shown to reduce the risk of stroke. In this review, we cover the role of statins in cerebrovascular disease through lipid-lowering mechanisms and other "pleiotropic" effects that provide protection against cerebrovascular events and potentially contribute to improve functional outcome after stroke.

Entities:  

Keywords:  Cholesterol; Intracerebral hemorrhage; Ischemic stroke; Lipids; Statin; Stroke

Year:  2016        PMID： 26920158     DOI： 10.1007/s11936-016-0448-8

Source DB:  PubMed          Journal:  Curr Treat Options Cardiovasc Med        ISSN： 1092-8464


  84 in total

1.  High-dose atorvastatin after stroke or transient ischemic attack.

Authors:  Pierre Amarenco; Julien Bogousslavsky; Alfred Callahan; Larry B Goldstein; Michael Hennerici; Amy E Rudolph; Henrik Sillesen; Lisa Simunovic; Michael Szarek; K M A Welch; Justin A Zivin
Journal:  N Engl J Med       Date:  2006-08-10       Impact factor: 91.245

2.  Use of intravascular ultrasound to compare effects of different strategies of lipid-lowering therapy on plaque volume and composition in patients with coronary artery disease.

Authors:  M Schartl; W Bocksch; D H Koschyk; W Voelker; K R Karsch; J Kreuzer; D Hausmann; S Beckmann; M Gross
Journal:  Circulation       Date:  2001-07-24       Impact factor: 29.690

3.  Involvement of Rho GTPases in the transcriptional inhibition of preproendothelin-1 gene expression by simvastatin in vascular endothelial cells.

Authors:  O Hernández-Perera; D Pérez-Sala; E Soria; S Lamas
Journal:  Circ Res       Date:  2000-09-29       Impact factor: 17.367

4.  Incidence, manifestations, and predictors of worsening white matter on serial cranial magnetic resonance imaging in the elderly: the Cardiovascular Health Study.

Authors:  W T Longstreth; Alice M Arnold; Norman J Beauchamp; Teri A Manolio; David Lefkowitz; Charles Jungreis; Calvin H Hirsch; Daniel H O'Leary; Curt D Furberg
Journal:  Stroke       Date:  2004-11-29       Impact factor: 7.914

5.  Cholesterol, coronary heart disease, and stroke in the Asia Pacific region.

Authors:  X Zhang; A Patel; H Horibe; Z Wu; F Barzi; A Rodgers; S MacMahon; M Woodward
Journal:  Int J Epidemiol       Date:  2003-08       Impact factor: 7.196

6.  Association of serum lipid indices with large artery atherosclerotic stroke.

Authors:  O Y Bang; J L Saver; D S Liebeskind; S Pineda; B Ovbiagele
Journal:  Neurology       Date:  2007-12-26       Impact factor: 9.910

7.  The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion.

Authors:  T J Anderson; I T Meredith; A C Yeung; B Frei; A P Selwyn; P Ganz
Journal:  N Engl J Med       Date:  1995-02-23       Impact factor: 91.245

8.  Platelet cytosolic Ca2+ and membrane dynamics in patients with primary hypercholesterolemia. Effects of pravastatin.

Authors:  K H Le Quan Sang; J Levenson; J L Megnien; A Simon; M A Devynck
Journal:  Arterioscler Thromb Vasc Biol       Date:  1995-06       Impact factor: 8.311

9.  Effects of statins on the progression of cerebral white matter lesion: Post hoc analysis of the ROCAS (Regression of Cerebral Artery Stenosis) study.

Authors:  Vincent C T Mok; Wynnie W M Lam; Yu Hua Fan; Adrian Wong; Ping Wing Ng; Tak Hon Tsoi; Vincent Yeung; Ka Sing Wong
Journal:  J Neurol       Date:  2009-03-01       Impact factor: 4.849

10.  Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group.

Authors:  J Shepherd; S M Cobbe; I Ford; C G Isles; A R Lorimer; P W MacFarlane; J H McKillop; C J Packard
Journal:  N Engl J Med       Date:  1995-11-16       Impact factor: 91.245
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  3 in total

1.  Hyperlipidemia is associated with lower risk of poststroke mortality independent of statin use: A population-based study.

Authors:  Samrat Yeramaneni; Dawn O Kleindorfer; Heidi Sucharew; Kathleen Alwell; Charles J Moomaw; Matthew L Flaherty; Daniel Woo; Opeolu Adeoye; Simona Ferioli; Felipe de Los Rios La Rosa; Sharyl Martini; Jason Mackey; Pooja Khatri; Brett M Kissela; Jane C Khoury
Journal:  Int J Stroke       Date:  2016-09-24       Impact factor: 5.266

2.  The Effect of Statins on C-Reactive Protein in Stroke Patients: A Systematic Review of Clinical Trials.

Authors:  Babak Alikiaii; Zahra Heidari; Mohammad Bagherniya; Gholamreza Askari; Thozhukat Sathyapalan; Amirhossein Sahebkar
Journal:  Mediators Inflamm       Date:  2021-08-27       Impact factor: 4.711

Review 3.  Minor Stroke and Transient Ischemic Attack: Research and Practice.

Authors:  Aleksandra Yakhkind; Ryan A McTaggart; Mahesh V Jayaraman; Matthew S Siket; Brian Silver; Shadi Yaghi
Journal:  Front Neurol       Date:  2016-06-10       Impact factor: 4.003
  3 in total

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