Literature DB >> 26917493

Coronally advanced flap with or without porcine collagen matrix for root coverage: a randomized clinical trial.

Ana Regina Oliveira Moreira1, Mauro Pedrine Santamaria2, Karina Gonzales Silvério1, Marcio Zaffalon Casati1, Francisco Humberto Nociti Junior1, Anton Sculean3, Enilson Antonio Sallum4.   

Abstract

OBJECTIVES: The objective of this study is to clinically evaluate the outcomes following treatment of single gingival recessions with either coronally advanced flap technique (CAF) alone or combined with a porcine collagen matrix graft (CM).
MATERIALS AND METHODS: This is a randomized parallel design clinical trial, including forty patients with single Miller Class I or II gingival recession, with a depth ≥ 2 mm and located at upper canines or premolars. The patients were randomly assigned to receive either CAF or CAF + CM. The primary outcome variable was gingival recession reduction (Rec Red).
RESULTS: Baseline recession depth was 3.14 ± 0.51 mm for CAF group and 3.16 ± 0.65 mm for CAF + CM group (p > 0.05). Both groups showed significant Rec Red (p < 0.05), up to 6 months. Rec Red for CAF + CM was 2.41 ± 0.73 mm and was 2.25 ± 0.50 mm for CAF alone (p > 0.05). Root coverage was 77.2 % in the CAF + CM group and 72.1 % in the CAF group (p > 0.05). Complete root coverage (CRC) was found in 40 % of the cases in the CAF + CM group and in 35 % of the sites treated with CAF. Keratinized tissue thickness (KTT) was 0.26 mm higher in CAF + CM group (p < 0.05).
CONCLUSIONS: It can be concluded that CAF + CM does not provide a superior recession reduction when compared to CAF; however, it may offer a small gain in KTT after 6 months. CLINICAL RELEVANCE: CAF + CM can be suggested as a valid therapeutic option to achieve root coverage and some increase in soft tissue thickness after 6 months.

Entities:  

Keywords:  Collagen/therapeutic use; Gingival recession/surgery; Root coverage; Treatment outcome

Mesh:

Substances:

Year:  2016        PMID: 26917493     DOI: 10.1007/s00784-016-1757-8

Source DB:  PubMed          Journal:  Clin Oral Investig        ISSN: 1432-6981            Impact factor:   3.573


  56 in total

1.  Root coverage using the coronally positioned flap with or without a subepithelial connective tissue graft.

Authors:  Robert Carvalho da Silva; Julio César Joly; Antonio Fernando Martorelli de Lima; Dimitris N Tatakis
Journal:  J Periodontol       Date:  2004-03       Impact factor: 6.993

2.  Gingival recession: epidemiology and risk indicators in a university dental hospital in Turkey.

Authors:  H Toker; H Ozdemir
Journal:  Int J Dent Hyg       Date:  2009-05       Impact factor: 2.477

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4.  Patient morbidity and root coverage outcome after subepithelial connective tissue and de-epithelialized grafts: a comparative randomized-controlled clinical trial.

Authors:  Giovanni Zucchelli; Monica Mele; Martina Stefanini; Claudio Mazzotti; Matteo Marzadori; Lucio Montebugnoli; Massimo de Sanctis
Journal:  J Clin Periodontol       Date:  2010-06-24       Impact factor: 8.728

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Journal:  J Periodontol       Date:  2005-02       Impact factor: 6.993

7.  Does placement of a connective tissue graft improve the outcomes of coronally advanced flap for coverage of single gingival recessions in upper anterior teeth? A multi-centre, randomized, double-blind, clinical trial.

Authors:  Pierpaolo Cortellini; Maurizio Tonetti; Carlo Baldi; Luca Francetti; Giulio Rasperini; Roberto Rotundo; Michele Nieri; Debora Franceschi; Antonella Labriola; Giovanpaolo Pini Prato
Journal:  J Clin Periodontol       Date:  2008-11-20       Impact factor: 8.728

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Journal:  J Clin Periodontol       Date:  1987-03       Impact factor: 8.728

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Journal:  J Clin Periodontol       Date:  1982-01       Impact factor: 8.728

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  4 in total

1.  Comparison between a xenogeneic dermal matrix and connective tissue graft for the treatment of multiple adjacent gingival recessions: a randomized controlled clinical trial.

Authors:  Jonathan Meza-Mauricio; Jônatas Cortez-Gianezzi; Poliana Mendes Duarte; Lorenzo Tavelli; Giulio Rasperini; Marcelo de Faveri
Journal:  Clin Oral Investig       Date:  2021-05-21       Impact factor: 3.573

2.  Coverage Root after Removing Peripheral Ossifying Fibroma: 5-Year Follow-Up Case Report.

Authors:  Paulo S G Henriques; Luciana S Okajima; Marcelo P Nunes; Victor A M Montalli
Journal:  Case Rep Dent       Date:  2016-11-07

Review 3.  A New Matrix for Soft Tissue Management.

Authors:  Daniele De Santis; Umberto Luciano; Paola Pancera; Giacomo Castegnaro; Christian Alberti; Federico Gelpi
Journal:  J Clin Med       Date:  2022-08-01       Impact factor: 4.964

4.  Cell Therapy Based on Gingiva-Derived Mesenchymal Stem Cells Seeded in a Xenogeneic Collagen Matrix for Root Coverage of RT1 Gingival Lesions: An In Vivo Experimental Study.

Authors:  Nerea Sanchez; Fabio Vignoletti; Ignacio Sanz-Martin; Alejandro Coca; Javier Nuñez; Estela Maldonado; Javier Sanz-Esporrin; Irene Hernando-Pradíes; Silvia Santamaría; David Herrera; Jose A Garcia-Sanz; Mariano Sanz
Journal:  Int J Mol Sci       Date:  2022-03-17       Impact factor: 5.923

  4 in total

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