| Literature DB >> 26917456 |
Sara Pusceddu1, Giuseppe Lo Russo1, Marianna Macerelli1, Claudia Proto1, Milena Vitali1, Diego Signorelli1, Monica Ganzinelli1, Paolo Scanagatta2, Leonardo Duranti2, Annalisa Trama3, Roberto Buzzoni1, Giuseppe Pelosi4, Ugo Pastorino2, Filippo de Braud1, Marina Chiara Garassino5.
Abstract
An estimated 20% to 30% of all neuroendocrine tumours originate in the bronchial tree and lungs. According to the 2015 World Health Organization categorization, these tumours are separated into four subtypes characterized by increasing biological aggressiveness: typical carcinoid, atypical carcinoid, large-cell neuroendocrine carcinoma and small-cell carcinoma. Although typical and atypical lung carcinoids account for less than 1-5% of all pulmonary malignancies, the incidence of these neoplasms has risen significantly in recent decades. Surgery is the treatment of choice for loco-regional disease but for advanced lung carcinoids there is no recognized standard of care and successful management requires a multidisciplinary approach. The aim of this review is to provide a useful guide for the clinical management of lung carcinoids.Entities:
Keywords: Atypical carcinoids; Lung carcinoids; Neuroendocrine tumours; Typical carcinoids
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Year: 2016 PMID： 26917456 DOI： 10.1016/j.critrevonc.2016.02.009
Source DB: PubMed Journal: Crit Rev Oncol Hematol ISSN： 1040-8428 Impact factor: 6.312