Literature DB >> 26916469

Anorexia Nervosa, Major Depression, and Suicide Attempts: Shared Genetic Factors.

Laura M Thornton1, Elisabeth Welch2, Melissa A Munn-Chernoff1, Paul Lichtenstein2, Cynthia M Bulik3,4,5.   

Abstract

The extent to which genetic and environmental factors influenced anorexia nervosa (AN), major depressive disorder (MDD), and suicide attempts (SA) were evaluated. Participants were 6,899 women from the Swedish Twin Study of Adults: Genes and Environment. A Cholesky decomposition assessed independent and overlapping genetic and environmental contributions to AN, MDD, and SA. Genetic factors accounted for a substantial amount of liability to all three traits; unique environmental factors accounted for most of the remaining liability. Shared genetic factors may underlie the coexpression of these traits. Results underscore the importance of assessing for signs of suicide among individuals with AN.
© 2016 The American Association of Suicidology.

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Year:  2016        PMID： 26916469      PMCID： PMC4996767          DOI： 10.1111/sltb.12235

Source DB:  PubMed          Journal:  Suicide Life Threat Behav        ISSN： 0363-0234


  41 in total

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Review 2.  Self-harm and suicide in adolescents.

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4.  Self-image and suicide in a Swedish national eating disorders clinical register.

Authors:  Cristin D Runfola; Laura M Thornton; Emily M Pisetsky; Cynthia M Bulik; Andreas Birgegård
Journal:  Compr Psychiatry       Date:  2013-11-19       Impact factor: 3.735

5.  Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication.

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6.  Suicide attempts in anorexia nervosa subtypes.

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Journal:  Compr Psychiatry       Date:  2010-10-30       Impact factor: 3.735

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Journal:  Compr Psychiatry       Date:  1995 Jan-Feb       Impact factor: 3.735

8.  Re-examining premature mortality in anorexia nervosa: a meta-analysis redux.

Authors:  Aparna Keshaviah; Katherine Edkins; Elizabeth R Hastings; Meera Krishna; Debra L Franko; David B Herzog; Jennifer J Thomas; Helen B Murray; Kamryn T Eddy
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9.  Suicide attempts in anorexia nervosa.

Authors:  Cynthia M Bulik; Laura Thornton; Andréa Poyastro Pinheiro; Katherine Plotnicov; Kelly L Klump; Harry Brandt; Steve Crawford; Manfred M Fichter; Katherine A Halmi; Craig Johnson; Allan S Kaplan; James Mitchell; Detlev Nutzinger; Michael Strober; Janet Treasure; D Blake Woodside; Wade H Berrettini; Walter H Kaye
Journal:  Psychosom Med       Date:  2008-02-06       Impact factor: 4.312

Review 10.  Epidemiology of eating disorders: incidence, prevalence and mortality rates.

Authors:  Frédérique R E Smink; Daphne van Hoeken; Hans W Hoek
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  17 in total

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Review 3.  Genetics of Anorexia Nervosa.

Authors:  Jessica H Baker; Katherine Schaumberg; Melissa A Munn-Chernoff
Journal:  Curr Psychiatry Rep       Date:  2017-09-22       Impact factor: 5.285

Review 4.  Genetic epidemiology of eating disorders.

Authors:  Cynthia M Bulik; Susan C Kleiman; Zeynep Yilmaz
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Review 5.  Roles, molecular mechanisms, and signaling pathways of TMEMs in neurological diseases.

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6.  Validity and utility of Hierarchical Taxonomy of Psychopathology (HiTOP): III. Emotional dysfunction superspectrum.

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Review 7.  Genetics and neurobiology of eating disorders.

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Review 8.  The Science Behind the Academy for Eating Disorders' Nine Truths About Eating Disorders.

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Journal:  Eur Eat Disord Rev       Date:  2017-10-02

Review 9.  Redefining phenotypes to advance psychiatric genetics: Implications from hierarchical taxonomy of psychopathology.

Authors:  Monika A Waszczuk; Nicholas R Eaton; Robert F Krueger; Alexander J Shackman; Irwin D Waldman; David H Zald; Benjamin B Lahey; Christopher J Patrick; Christopher C Conway; Johan Ormel; Steven E Hyman; Eiko I Fried; Miriam K Forbes; Anna R Docherty; Robert R Althoff; Bo Bach; Michael Chmielewski; Colin G DeYoung; Kelsie T Forbush; Michael Hallquist; Christopher J Hopwood; Masha Y Ivanova; Katherine G Jonas; Robert D Latzman; Kristian E Markon; Stephanie N Mullins-Sweatt; Aaron L Pincus; Ulrich Reininghaus; Susan C South; Jennifer L Tackett; David Watson; Aidan G C Wright; Roman Kotov
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10.  The Association of Malnutrition, illness duration, and pre-morbid weight status with anxiety and depression symptoms in adolescents and young adults with restrictive eating disorders: a cross-sectional study.

Authors:  Jessica A Lin; Grace Jhe; Julia A Vitagliano; Carly E Milliren; Rebecca Spigel; Elizabeth R Woods; Sara F Forman; Tracy K Richmond
Journal:  J Eat Disord       Date:  2021-05-17
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