| Literature DB >> 26916119 |
Abstract
Optimal control methods are applied to a deterministic mathematical model to characterize the factors contributing to the replacement of hospital-acquired methicillin-resistant Staphylococcus aureus (HA-MRSA) with community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA), and quantify the effectiveness of three interventions aimed at limiting the spread of CA-MRSA in healthcare settings. Characterizations of the optimal control strategies are established, and numerical simulations are provided to illustrate the results.Entities:
Keywords: 49K15; 92B05; 92D30; MRSA; Optimal control; decolonization; screening
Mesh:
Year: 2016 PMID: 26916119 DOI: 10.1080/17513758.2016.1151564
Source DB: PubMed Journal: J Biol Dyn ISSN: 1751-3758 Impact factor: 2.179