| Literature DB >> 26916052 |
Junning Chen1, Liangjian Chen2, Che-Cheng Chang1, Zhongpu Zhang1, Wei Li1, Michael V Swain3, Qing Li1.
Abstract
Design of prosthetic implants to ensure rapid and stable osseointegration remains a significant challenge, and continuous efforts have been directed to new implant materials, structures and morphology. This paper aims to develop and characterise a porous titanium dental implant fabricated by metallic powder injection-moulding. The surface morphology of the specimens was first examined with a scanning electron microscope (SEM), followed by microscopic computerised tomography (μ-CT) scanning to capture its 3D microscopic features non-destructively. The nature of porosity and pore sizes were determined statistically. A homogenisation technique based on the Hills-energy theorem was adopted to evaluate its directional elastic moduli, and the conservation of mass theorem was employed to quantify the oxygen diffusivity for bio-transportation feature. This porous medium was found to have pore sizes varying from 50 to 400 µm and the average porosity of 46.90 ± 1.83%. The anisotropic principal elastic moduli were found fairly close to the upper range of cortical bone, and the directional diffusivities could potentially enable radial osseous tissue ingrowth and vascularisation. This porous titanium successfully reduces the elastic modulus mismatch between implant and bone for dental and orthopaedic applications, and provides improved capacity for transporting oxygen, nutrient and waste for pre-vascular network formation.Entities:
Keywords: anisotropic elasticity; diffusivity; homogenisation; injection moulding; osseointegration; porous implant
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Year: 2016 PMID: 26916052 DOI: 10.1002/cnm.2779
Source DB: PubMed Journal: Int J Numer Method Biomed Eng ISSN: 2040-7939 Impact factor: 2.747