S Rico Martín1, J M de Nicolás Jiménez2, S L Moyano Calvente3, M V Mogollón Jiménez4, J Vega Fernández4, J F Calderón García1, M A Bacaicoa Lopez de Sabando5, M Tardio6, J F Sánchez Muñoz-Torrero7. 1. Facultad de Enfermería y Terapia Ocupacional, Universidad de Extremadura, Cáceres, España. 2. Centro de Salud Jaraicejo, Jaraicejo, Cáceres, España. 3. Servicio de Radiología, Hospital San Pedro de Alcántara, Cáceres, España. 4. Servicio de Cardiología, Hospital San Pedro de Alcántara, Cáceres, España. 5. Centro de Salud Manuel Encinas, Cáceres, España. 6. Escuela de Ingenería Industrial. Universidad de Extremadura, Badajoz, España. 7. Servicio de Medicina Interna, Hospital San Pedro de Alcántara, Cáceres, España. Electronic address: juanf.sanchezm@gmail.com.
Abstract
OBJECTIVE: The pulse wave velocity (PWV) in the great arteries is an indicator of vascular risk. Our objective was to identify the PWV index between the arms and legs that best correlates with the coronary calcium quantification (CCQ) and to compare it with other methods. MATERIAL AND METHODS: Eight-one patients without vascular disease underwent the following measurements: CCQ; carotid intima-media thickness (IMT); carotid-femoral PWV (cfPWV), using COMPLIOR; and PWV in the arms and legs, with our own device (abiPWV, ankle brachial index PWV). RESULTS: The difference in PWVs between the leg and arm (l-a PWV) measured with abiPWV was the index that best correlated with CCQ (r=0.401, P<.001). The correlation between IMT and CCQ and between CF-PWV and CCQ were r=0.366, P=.001; and r=0.385, P=.001, respectively. For a CCQ score higher than 100 as a marker of significant coronary arteriosclerosis, the areas under the curve for l-a PWV, IMT and cfPWV were 0.721 (P=.002), 0.758 (P<.001) and 0.636 (P=.058), respectively. CONCLUSIONS: For patients without vascular disease, the l-a PWV measured with abiPWV appears to be the index that best correlates with the CCQ. This association is comparable to that between IMT and CCQ and between cfPWV and CCQ. The abiPWV is an easy-to-use device that can help improve vascular risk stratification.
OBJECTIVE: The pulse wave velocity (PWV) in the great arteries is an indicator of vascular risk. Our objective was to identify the PWV index between the arms and legs that best correlates with the coronary calcium quantification (CCQ) and to compare it with other methods. MATERIAL AND METHODS: Eight-one patients without vascular disease underwent the following measurements: CCQ; carotid intima-media thickness (IMT); carotid-femoral PWV (cfPWV), using COMPLIOR; and PWV in the arms and legs, with our own device (abiPWV, ankle brachial index PWV). RESULTS: The difference in PWVs between the leg and arm (l-a PWV) measured with abiPWV was the index that best correlated with CCQ (r=0.401, P<.001). The correlation between IMT and CCQ and between CF-PWV and CCQ were r=0.366, P=.001; and r=0.385, P=.001, respectively. For a CCQ score higher than 100 as a marker of significant coronary arteriosclerosis, the areas under the curve for l-a PWV, IMT and cfPWV were 0.721 (P=.002), 0.758 (P<.001) and 0.636 (P=.058), respectively. CONCLUSIONS: For patients without vascular disease, the l-a PWV measured with abiPWV appears to be the index that best correlates with the CCQ. This association is comparable to that between IMT and CCQ and between cfPWV and CCQ. The abiPWV is an easy-to-use device that can help improve vascular risk stratification.
Keywords:
Cardiovascular risk; Coronary calcium quantification; Cuantificación de calcio coronario; Grosos de íntima media; Intima-media thickness; Pulse wave velocity; Riesgo cardiovascular; Velocidad de onda de pulso
Authors: Juan Francisco Sánchez Muñoz-Torrero; Julián Fernando Calderón-García; Jorge Manuel De Nicolás-Jiménez; Luis García-Ortiz; Enrique Rodilla-Salas; Manuel Angel Gómez-Marcos; Carmen Suárez-Fernandez; Sergio Cordovilla-Guardia; Sergio Rico-Martín Journal: PLoS One Date: 2018-11-01 Impact factor: 3.240
Authors: Julián F Calderón García; Juan F Sánchez Muñoz-Torrero; Sergio Rico Martín; Valentina Vassilenko; Jorge M de Nicolás Jiménez; Purificación Rey Sánchez; Andreia Serrano; Mariana Martínez Alvarez Journal: BMJ Open Date: 2020-10-20 Impact factor: 2.692