Literature DB >> 26914638

High-Throughput Measurement of Binding Kinetics by mRNA Display and Next-Generation Sequencing.

Farzad Jalali-Yazdi1, Lan Huong Lai2, Terry T Takahashi2, Richard W Roberts3,4.   

Abstract

There is great demand for high-throughput methods to characterize ligand affinity. By combining mRNA display with next-generation sequencing, we determined the kinetic on- and off-rates for over twenty thousand ligands without the need for synthesis or purification of individual members. Our results are reproducible and as accurate as those obtained with other methods of affinity measurement.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  affinity measurements; dissociation constants; high-throughput screenings; kinetics; protein-protein interactions

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Year:  2016        PMID： 26914638      PMCID： PMC4834215          DOI： 10.1002/anie.201600077

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  15 in total

1.  Simultaneous measurement of 10,000 protein-ligand affinity constants using microarray-based kinetic constant assays.

Authors:  James P Landry; Yiyan Fei; Xiangdong Zhu
Journal:  Assay Drug Dev Technol       Date:  2011-12-22       Impact factor: 1.738

2.  Phage antibodies: filamentous phage displaying antibody variable domains.

Authors:  J McCafferty; A D Griffiths; G Winter; D J Chiswell
Journal:  Nature       Date:  1990-12-06       Impact factor: 49.962

3.  General, Label-Free Method for Determining K(d) and Ligand Concentration Simultaneously.

Authors:  Farzad Jalali-Yazdi; Terry T Takahashi; Richard W Roberts
Journal:  Anal Chem       Date:  2015-11-13       Impact factor: 6.986

4.  A novel approach to protein expression profiling using antibody microarrays combined with surface plasmon resonance technology.

Authors:  Kazue Usui-Aoki; Kiyo Shimada; Mihoko Nagano; Makoto Kawai; Hisashi Koga
Journal:  Proteomics       Date:  2005-06       Impact factor: 3.984

5.  High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays.

Authors:  Dina Wassaf; Guannan Kuang; Kris Kopacz; Qi-Long Wu; Que Nguyen; Mark Toews; Janja Cosic; Judith Jacques; Steve Wiltshire; Jeremy Lambert; Csaba C Pazmany; Shannon Hogan; Robert C Ladner; Andrew E Nixon; Daniel J Sexton
Journal:  Anal Biochem       Date:  2006-02-10       Impact factor: 3.365

6.  An in vitro polysome display system for identifying ligands from very large peptide libraries.

Authors:  L C Mattheakis; R R Bhatt; W J Dower
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-13       Impact factor: 11.205

7.  RNA-peptide fusions for the in vitro selection of peptides and proteins.

Authors:  R W Roberts; J W Szostak
Journal:  Proc Natl Acad Sci U S A       Date:  1997-11-11       Impact factor: 11.205

8.  High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis.

Authors:  B C Cunningham; J A Wells
Journal:  Science       Date:  1989-06-02       Impact factor: 47.728

9.  Single-round, multiplexed antibody mimetic design through mRNA display.

Authors:  C Anders Olson; Jeff Nie; Jonathan Diep; Ibrahim Al-Shyoukh; Terry T Takahashi; Laith Q Al-Mawsawi; Jennifer M Bolin; Angela L Elwell; Scott Swanson; Ron Stewart; James A Thomson; H Tom Soh; Richard W Roberts; Ren Sun
Journal:  Angew Chem Int Ed Engl       Date:  2012-11-04       Impact factor: 15.336

10.  High throughput solution-based measurement of antibody-antigen affinity and epitope binning.

Authors:  Patricia Estep; Felicia Reid; Claire Nauman; Yuqi Liu; Tingwan Sun; Joanne Sun; Yingda Xu
Journal:  MAbs       Date:  2013 Mar-Apr       Impact factor: 5.857
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  12 in total

1.  Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display.

Authors:  David E Hacker; Jan Hoinka; Emil S Iqbal; Teresa M Przytycka; Matthew C T Hartman
Journal:  ACS Chem Biol       Date:  2017-02-01       Impact factor: 5.100

2.  Multiplex Aptamer Discovery through Apta-Seq and Its Application to ATP Aptamers Derived from Human-Genomic SELEX.

Authors:  Michael M Abdelsayed; Bao T Ho; Michael M K Vu; Julio Polanco; Robert C Spitale; Andrej Lupták
Journal:  ACS Chem Biol       Date:  2017-07-11       Impact factor: 5.100

3.  Analysis of in vitro evolution reveals the underlying distribution of catalytic activity among random sequences.

Authors:  Abe Pressman; Janina E Moretti; Gregory W Campbell; Ulrich F Müller; Irene A Chen
Journal:  Nucleic Acids Res       Date:  2017-08-21       Impact factor: 16.971

4.  Encapsulation of ribozymes inside model protocells leads to faster evolutionary adaptation.

Authors:  Yei-Chen Lai; Ziwei Liu; Irene A Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2021-05-25       Impact factor: 11.205

Review 5.  Directing evolution of novel ligands by mRNA display.

Authors:  Golnaz Kamalinia; Brian J Grindel; Terry T Takahashi; Steven W Millward; Richard W Roberts
Journal:  Chem Soc Rev       Date:  2021-06-24       Impact factor: 60.615

6.  Mapping a Systematic Ribozyme Fitness Landscape Reveals a Frustrated Evolutionary Network for Self-Aminoacylating RNA.

Authors:  Abe D Pressman; Ziwei Liu; Evan Janzen; Celia Blanco; Ulrich F Müller; Gerald F Joyce; Robert Pascal; Irene A Chen
Journal:  J Am Chem Soc       Date:  2019-04-05       Impact factor: 15.419

7.  α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor.

Authors:  Aaron L Nichols; Kaori Noridomi; Christopher R Hughes; Farzad Jalali-Yazdi; J Brek Eaton; Lan Huong Lai; Gaurav Advani; Ronald J Lukas; Henry A Lester; Lin Chen; Richard W Roberts
Journal:  ACS Chem Biol       Date:  2018-08-13       Impact factor: 5.100

8.  Enhancing the throughput and multiplexing capabilities of next generation sequencing for efficient implementation of pooled shRNA and CRISPR screens.

Authors:  Md Fahmid Islam; Atsushi Watanabe; Lai Wong; Conor Lazarou; Frederick S Vizeacoumar; Omar Abuhussein; Wayne Hill; Maruti Uppalapati; C Ronald Geyer; Franco J Vizeacoumar
Journal:  Sci Rep       Date:  2017-04-21       Impact factor: 4.379

9.  Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2).

Authors:  Carolina Garri; Shannon Howell; Katrin Tiemann; Aleczandria Tiffany; Farzad Jalali-Yazdi; Mario M Alba; Jonathan E Katz; Terry T Takahashi; Ralf Landgraf; Mitchell E Gross; Richard W Roberts; Kian Kani
Journal:  Oncotarget       Date:  2018-06-08

10.  Photocrosslinking of cDNA Display Molecules with Their Target Proteins as a New Strategy for Peptide Selection.

Authors:  Takuya Terai; Tomoyuki Koike; Naoto Nemoto
Journal:  Molecules       Date:  2020-03-24       Impact factor: 4.411
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