Literature DB >> 26914449

High proportion of HIV late presenters at an academic tertiary care center in northern Germany confirms the results of several cohorts in Germany: time to put better HIV screening efforts on the national agenda?

Guido Schäfer1, Benno Kreuels1, Stefan Schmiedel1, Sandra Hertling1, Anja Hüfner1, Olaf Degen1, Jan van Lunzen1,2, Julian Schulze Zur Wiesch3.   

Abstract

165 treatment-naive patients who first presented at the infectious disease clinic of the University Medical Center Hamburg-Eppendorf from 2009 to 2011 were retrospectively analyzed with emphasis on patients with late presentation (LP). In line with other recent German reports, there was a large proportion of 105 of the 165 treatment-naïve patients (63.6 %) who presented late. Old age, heterosexual transmission risk and migrant background were associated risk factors for late presentation. Thus, further intensified national efforts like the HIV in Europe initiative are needed to identify such patients at high risk for HIV infection.

Entities:  

Keywords:  Cohort study; Epidemiology; Germany; HIV; Late presentation

Mesh:

Year:  2016        PMID: 26914449     DOI: 10.1007/s15010-016-0880-4

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  12 in total

1.  Essentials from the 2015 European AIDS Clinical Society (EACS) guidelines for the treatment of adult HIV-positive persons.

Authors:  L Ryom; C Boesecke; V Gisler; C Manzardo; J K Rockstroh; M Puoti; H Furrer; J M Miro; J M Gatell; A Pozniak; G Behrens; M Battegay; J D Lundgren
Journal:  HIV Med       Date:  2015-11-08       Impact factor: 3.180

2.  Late presentation to HIV/AIDS testing, treatment or continued care: clarifying the use of CD4 evaluation in the consensus definition.

Authors:  S MacCarthy; D R Bangsberg; G Fink; M Reich; S Gruskin
Journal:  HIV Med       Date:  2013-09-11       Impact factor: 3.180

3.  Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration.

Authors:  Colette J Smith; Lene Ryom; Rainer Weber; Philippe Morlat; Christian Pradier; Peter Reiss; Justyna D Kowalska; Stephane de Wit; Matthew Law; Wafaa el Sadr; Ole Kirk; Nina Friis-Moller; Antonella d'Arminio Monforte; Andrew N Phillips; Caroline A Sabin; Jens D Lundgren
Journal:  Lancet       Date:  2014-07-19       Impact factor: 79.321

4.  Late presentation of HIV infection: a consensus definition.

Authors:  A Antinori; T Coenen; D Costagiola; N Dedes; M Ellefson; J Gatell; E Girardi; M Johnson; O Kirk; J Lundgren; A Mocroft; A D'Arminio Monforte; A Phillips; D Raben; J K Rockstroh; C Sabin; A Sönnerborg; F De Wolf
Journal:  HIV Med       Date:  2011-01       Impact factor: 3.180

5.  Late presentation for HIV diagnosis and care in Germany.

Authors:  A Zoufaly; M an der Heiden; U Marcus; C Hoffmann; Hj Stellbrink; L Voss; J van Lunzen; O Hamouda
Journal:  HIV Med       Date:  2011-11-07       Impact factor: 3.180

6.  Lack of awareness in both patients and physicians contributes to a high rate of late presentation in a South West German HIV patient cohort.

Authors:  J M Kittner; L von Bialy; J Wiltink; T Thomaidis; B Gospodinov; A Rieke; F Katz; T Discher; K Rath; B Claus; G Held; G Friese; B Schappert; M Schuchmann; P R Galle
Journal:  Infection       Date:  2015-01-20       Impact factor: 3.553

7.  Late presentation of HIV despite earlier opportunities for detection, experience from an Irish tertiary referral institution.

Authors:  D O'Shea; M Ebrahim; A Egli; D Redmond; S McConkey
Journal:  Ir J Med Sci       Date:  2013-01-16       Impact factor: 1.568

8.  Analysis of risk factors for late presentation in a cohort of HIV-infected patients in Dresden: positive serology for syphilis in MSM is a determinant for earlier HIV diagnosis.

Authors:  P Spornraft-Ragaller; U Boashie; V Stephan; J Schmitt
Journal:  Infection       Date:  2013-06-01       Impact factor: 3.553

9.  Clinical and epidemiological features of HIV/AIDS infection among migrants at first access to healthcare services as compared to Italian patients in Italy: a retrospective multicentre study, 2000-2010.

Authors:  G Sulis; I El Hamad; M Fabiani; S Rusconi; F Maggiolo; G Guaraldi; G Bozzi; C Bernardini; M Lichtner; C Stentarelli; L Carenzi; D Francisci; A Saracino; F Castelli
Journal:  Infection       Date:  2014-06-29       Impact factor: 3.553

10.  Late presenters in an HIV surveillance system in Italy during the period 1992-2006.

Authors:  Vanni Borghi; Enrico Girardi; Stefania Bellelli; Claudio Angeletti; Cristina Mussini; Kholoud Porter; Roberto Esposito
Journal:  J Acquir Immune Defic Syndr       Date:  2008-11-01       Impact factor: 3.731

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  4 in total

1.  Refugees and family-reunified immigrants have a high incidence of HIV diagnosis and late presentation compared with Danish born: a nationwide register-based cohort study.

Authors:  Laura Deen; Susan Cowan; Christian Wejse; Jørgen Holm Petersen; Marie Norredam
Journal:  Infection       Date:  2018-07-03       Impact factor: 3.553

2.  Impact of refugee influx on the epidemiology of late-presenting HIV-infected pregnant women and mother-to-child transmission: comparing a southern and northern medical centre in Germany.

Authors:  Katharina Singer; Ulf Schulze-Sturm; Irene Alba-Alejandre; Bettina Hollwitz; Thi Thanh Truc Nguyen; Franz Sollinger; Josef Eberle; Johannes Hübner; Robin Kobbe; Orsolya Genzel-Boroviczény; Ulrich von Both
Journal:  Infection       Date:  2019-06-12       Impact factor: 3.553

3.  Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study).

Authors:  Guido Schäfer; Christian Hoffmann; Keikawus Arasteh; Dirk Schürmann; Christoph Stephan; Björn Jensen; Matthias Stoll; Johannes R Bogner; Gerd Faetkenheuer; Jürgen Rockstroh; Hartwig Klinker; Georg Härter; Albrecht Stöhr; Olaf Degen; Eric Freiwald; Anja Hüfner; Sabine Jordan; Julian Schulze Zur Wiesch; Marylyn Addo; Ansgar W Lohse; Jan van Lunzen; Stefan Schmiedel
Journal:  AIDS Res Ther       Date:  2019-11-15       Impact factor: 2.250

4.  Basic knowledge among GP trainees regarding HIV pre- and post-exposition-prophylaxis.

Authors:  Christian Flössner; Meri Avetisyan; Thomas Frese
Journal:  J Family Med Prim Care       Date:  2021-09-30
  4 in total

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