Literature DB >> 26913959

Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration.

Pingqiang Cai1, Michael Layani2, Wan Ru Leow1, Shahrouz Amini1, Zhiyuan Liu1, Dianpeng Qi1, Benhui Hu1, Yun-Long Wu1, Ali Miserez1, Shlomo Magdassi2, Xiaodong Chen1.   

Abstract

A platform of mechanotactic hybrids is established by projecting lateral gradients of apparent interfacial stiffness onto the planar surface of a compliant hydrogel layer using an underlying rigid substrate with microstructures inherited from 3D printed molds. Using this platform, the mechanistic coupling of epithelial migration with the stiffness of the extracellular matrix (ECM) is found to be independent of the interfacial compositional and topographical cues.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keywords:  3D printing; bio-inspired materials; collective cell migration; mechanotaxis; stiffness gradient

Mesh：

Substances：

Year:  2016        PMID： 26913959     DOI： 10.1002/adma.201505300

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  6 in total

1.  Soft conductive micropillar electrode arrays for biologically relevant electrophysiological recording.

Authors:  Yuxin Liu; Allister F McGuire; Hsin-Ya Lou; Thomas L Li; Jeffrey B-H Tok; Bianxiao Cui; Zhenan Bao
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-30       Impact factor: 11.205

Review 2.  3D printing for the design and fabrication of polymer-based gradient scaffolds.

Authors:  Laura G Bracaglia; Brandon T Smith; Emma Watson; Navein Arumugasaamy; Antonios G Mikos; John P Fisher
Journal:  Acta Biomater       Date:  2017-03-22       Impact factor: 8.947

3.  Bioinspired Mechano-Sensitive Macroporous Ceramic Sponge for Logical Drug and Cell Delivery.

Authors:  Changlu Xu; Zhihao Wei; Huajian Gao; Yanjie Bai; Huiling Liu; Huilin Yang; Yuekun Lai; Lei Yang
Journal:  Adv Sci (Weinh)       Date:  2017-04-27       Impact factor: 16.806

4.  Electrospun Pectin-Polyhydroxybutyrate Nanofibers for Retinal Tissue Engineering.

Authors:  Siew Yin Chan; Benjamin Qi Yu Chan; Zengping Liu; Bhav Harshad Parikh; Kangyi Zhang; Qianyu Lin; Xinyi Su; Dan Kai; Wee Sim Choo; David James Young; Xian Jun Loh
Journal:  ACS Omega       Date:  2017-12-14

5.  Locally coupled electromechanical interfaces based on cytoadhesion-inspired hybrids to identify muscular excitation-contraction signatures.

Authors:  Pingqiang Cai; Changjin Wan; Liang Pan; Naoji Matsuhisa; Ke He; Zequn Cui; Wei Zhang; Chengcheng Li; Jianwu Wang; Jing Yu; Ming Wang; Ying Jiang; Geng Chen; Xiaodong Chen
Journal:  Nat Commun       Date:  2020-05-04       Impact factor: 14.919

Review 6.  Gradient Material Strategies for Hydrogel Optimization in Tissue Engineering Applications.

Authors:  Laura A Smith Callahan
Journal:  High Throughput       Date:  2018-01-04
  6 in total

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